Blue Jays Roster & Staff
Transactions
| Date | Transaction |
| 09/29/21 | Toronto Blue Jays optioned RHP Anthony Castro to Buffalo Bisons. |
| 09/29/21 | Toronto Blue Jays selected the contract of RHP Jacob Barnes from Buffalo Bisons. |
| 09/29/21 | Toronto Blue Jays released 3B Jake Lamb. |
| 09/28/21 | Toronto Blue Jays optioned LHP Ryan Borucki to Buffalo Bisons. |
| 09/28/21 | Toronto Blue Jays optioned LHP Kirby Snead to Buffalo Bisons. |
| 09/28/21 | Toronto Blue Jays activated 2B Cavan Biggio. |
| 09/28/21 | Toronto Blue Jays activated LHP Hyun Jin Ryu from the 10-day injured list. |
| 09/26/21 | Toronto Blue Jays activated LHP Ryan Borucki. |
| 09/25/21 | Toronto Blue Jays placed RHP Joakim Soria on the 10-day injured list. |
| 09/25/21 | Toronto Blue Jays recalled LHP Kirby Snead from Buffalo Bisons. |
| 09/24/21 | Toronto Blue Jays placed RHP Thomas Hatch on the 10-day injured list. Right hamstring tendonitis. |
| 09/24/21 | Toronto Blue Jays activated RHP Joakim Soria. |
| 09/24/21 | LHP Ryan Borucki roster status changed by Toronto Blue Jays. |
| 09/24/21 | Toronto Blue Jays activated 2B Santiago Espinal. |
| 09/24/21 | Toronto Blue Jays optioned SS Kevin Smith to Buffalo Bisons. |
| 09/23/21 | Toronto Blue Jays recalled RHP Thomas Hatch from Buffalo Bisons. |
| 09/23/21 | Toronto Blue Jays activated 2B Breyvic Valera from the 10-day injured list. |
| 09/23/21 | Toronto Blue Jays designated 3B Jake Lamb for assignment. |
| 09/23/21 | Toronto Blue Jays optioned LHP Tayler Saucedo to Buffalo Bisons. |
| 09/22/21 | Toronto Blue Jays recalled SS Kevin Smith from Buffalo Bisons. |
| 09/22/21 | Toronto Blue Jays optioned LHP Anthony Kay to Buffalo Bisons. |
| 09/22/21 | Toronto Blue Jays placed 2B Breyvic Valera on the 10-day injured list. |
| 09/19/21 | Toronto Blue Jays recalled LHP Tayler Saucedo from Buffalo Bisons. |
| 09/19/21 | Toronto Blue Jays placed LHP Hyun Jin Ryu on the 10-day injured list. Neck tightness. |
| 09/18/21 | Toronto Blue Jays sent 2B Santiago Espinal on a rehab assignment to Buffalo Bisons. |
| 09/18/21 | RHP Joakim Soria roster status changed by Toronto Blue Jays. |
| 09/18/21 | Toronto Blue Jays recalled RHP Anthony Castro from Buffalo Bisons. |
| 09/13/21 | Toronto Blue Jays optioned RHP Trent Thornton to Buffalo Bisons. |
| 09/13/21 | Toronto Blue Jays recalled LHP Ryan Borucki from Buffalo Bisons. |
| 09/12/21 | Toronto Blue Jays optioned RHP Thomas Hatch to Buffalo Bisons. |
| 09/12/21 | Toronto Blue Jays recalled RHP Trent Thornton from Buffalo Bisons. |
| 09/12/21 | Toronto Blue Jays optioned RHP Anthony Castro to Buffalo Bisons. |
| 09/11/21 | Toronto Blue Jays recalled RHP Thomas Hatch from Buffalo Bisons. |
| 09/11/21 | Toronto Blue Jays optioned LHP Tayler Saucedo to Buffalo Bisons. |
| 09/11/21 | Toronto Blue Jays recalled RHP Anthony Castro from Buffalo Bisons. |
| 09/11/21 | Toronto Blue Jays sent 2B Cavan Biggio on a rehab assignment to Buffalo Bisons. |
| 09/10/21 | Toronto Blue Jays activated RHP Ross Stripling. |
| 09/10/21 | Toronto Blue Jays optioned SS Kevin Smith to Buffalo Bisons. |
| 09/08/21 | Toronto Blue Jays activated RHP Julian Merryweather. |
| 09/08/21 | Toronto Blue Jays optioned RHP Bryan Baker to Buffalo Bisons. |
| 09/08/21 | Toronto Blue Jays signed C Jommer Hernandez. |
| 09/08/21 | Toronto Blue Jays placed LHP Anthony Kay on the 10-day injured list. |
| 09/07/21 | Toronto Blue Jays sent RHP Ross Stripling on a rehab assignment to Buffalo Bisons. |
| 09/06/21 | Pittsburgh Pirates claimed RHP Connor Overton off waivers from Toronto Blue Jays. |
| 09/04/21 | Toronto Blue Jays activated 3B Jake Lamb. |
| 09/04/21 | Toronto Blue Jays optioned LHP Kirby Snead to Buffalo Bisons. |
| 09/03/21 | Toronto Blue Jays sent RHP A.J. Cole outright to Buffalo Bisons. |
| 09/03/21 | Toronto Blue Jays designated RHP Connor Overton for assignment. |
| 09/03/21 | Toronto Blue Jays recalled LHP Kirby Snead from Buffalo Bisons. |
| 09/03/21 | Toronto Blue Jays claimed 3B Jake Lamb off waivers from Chicago White Sox. |
| 09/02/21 | New York Mets claimed LHP Brad Hand off waivers from Toronto Blue Jays. |
| 09/01/21 | Toronto Blue Jays traded LHP Yaifer Perdomo and C J.J. D'Orazio to Arizona Diamondbacks. |
| 09/01/21 | Toronto Blue Jays traded LHP Yaifer Perdomo and C J.J. D'Orazio to Arizona Diamondbacks. |
| 09/01/21 | Toronto Blue Jays optioned RHP Anthony Castro to Buffalo Bisons. |
| 09/01/21 | Toronto Blue Jays recalled RHP Nate Pearson from Buffalo Bisons. |
| 09/01/21 | Toronto Blue Jays selected the contract of RHP Bryan Baker from Buffalo Bisons. |