Blue Jays Roster & Staff
Transactions
| Date | Transaction |
| 07/31/21 | Toronto Blue Jays released RHP Tyler Chatwood. |
| 07/31/21 | Toronto Blue Jays signed 3B Damiano Palmegiani. |
| 07/31/21 | Toronto Blue Jays optioned RHP Trent Thornton to Buffalo Bisons. |
| 07/31/21 | Toronto Blue Jays signed LHP Cooper Benson. |
| 07/31/21 | Toronto Blue Jays sent RHP Carl Edwards Jr. on a rehab assignment to FCL Blue Jays. |
| 07/31/21 | Toronto Blue Jays activated RHP Alek Manoah from the 10-day injured list. |
| 07/30/21 | Toronto Blue Jays designated RHP Tyler Chatwood for assignment. |
| 07/30/21 | Toronto Blue Jays optioned LHP Kirby Snead to Buffalo Bisons. |
| 07/30/21 | LHP Tayler Saucedo changed number to 54. |
| 07/30/21 | Toronto Blue Jays designated CF Jonathan Davis for assignment. |
| 07/30/21 | Minnesota Twins traded RHP Jose Berrios to Toronto Blue Jays for SS Austin Martin and RHP Simeon Woods Richardson. |
| 07/30/21 | Minnesota Twins traded RHP Jose Berrios to Toronto Blue Jays for SS Austin Martin and RHP Simeon Woods Richardson. |
| 07/30/21 | Minnesota Twins traded RHP Jose Berrios to Toronto Blue Jays for SS Austin Martin and RHP Simeon Woods Richardson. |
| 07/30/21 | Toronto Blue Jays activated LHP Brad Hand. |
| 07/30/21 | Arizona Diamondbacks traded RHP Joakim Soria to Toronto Blue Jays for Player To Be Named Later and Player To Be Named Later. |
| 07/29/21 | Washington Nationals traded LHP Brad Hand to Toronto Blue Jays for C Riley Adams. |
| 07/29/21 | Washington Nationals traded LHP Brad Hand to Toronto Blue Jays for C Riley Adams. |
| 07/29/21 | Toronto Blue Jays optioned RHP Patrick Murphy to Buffalo Bisons. |
| 07/28/21 | Toronto Blue Jays sent LF Corey Dickerson on a rehab assignment to Buffalo Bisons. |
| 07/28/21 | Toronto Blue Jays recalled RHP Patrick Murphy from Buffalo Bisons. |
| 07/27/21 | Toronto Blue Jays sent LHP Nick Allgeyer outright to Buffalo Bisons. |
| 07/26/21 | Toronto Blue Jays selected the contract of LHP Kirby Snead from Buffalo Bisons. |
| 07/26/21 | Toronto Blue Jays designated RHP Jacob Barnes for assignment. |
| 07/25/21 | Toronto Blue Jays recalled RHP Trent Thornton from Buffalo Bisons. |
| 07/25/21 | Toronto Blue Jays optioned CF Jonathan Davis to Buffalo Bisons. |
| 07/25/21 | Toronto Blue Jays traded RHP T.J. Zeuch to St. Louis Cardinals for cash. |
| 07/24/21 | Toronto Blue Jays sent LHP Tommy Milone on a rehab assignment to Buffalo Bisons. |
| 07/23/21 | Toronto Blue Jays activated 2B Breyvic Valera from the bereavement list. |
| 07/23/21 | Toronto Blue Jays placed C Danny Jansen on the 10-day injured list. Right hamstring strain. |
| 07/23/21 | Toronto Blue Jays recalled C Alejandro Kirk, , , and from Buffalo Bisons. |
| 07/23/21 | Toronto Blue Jays optioned RHP Patrick Murphy to Buffalo Bisons. |
| 07/21/21 | Toronto Blue Jays signed RHP Hunter Gregory. |
| 07/21/21 | Toronto Blue Jays signed C Juan Gonzalez. |
| 07/21/21 | Toronto Blue Jays signed RHP Chad Dallas. |
| 07/21/21 | Toronto Blue Jays signed LHP Jimmy Burnette. |
| 07/21/21 | Toronto Blue Jays signed OF Garrett Spain. |
| 07/21/21 | Toronto Blue Jays sent RHP Anthony Castro on a rehab assignment to Buffalo Bisons. |
| 07/21/21 | Toronto Blue Jays signed RHP Hayden Juenger. |
| 07/21/21 | Toronto Blue Jays signed RHP Conor Larkin. |
| 07/21/21 | Toronto Blue Jays recalled RHP Patrick Murphy from Buffalo Bisons. |
| 07/21/21 | Toronto Blue Jays signed free agent RHP Justin Kelly to a minor league contract. |
| 07/21/21 | Toronto Blue Jays signed free agent LHP Harry Rutkowski to a minor league contract. |
| 07/21/21 | Toronto Blue Jays signed LHP Trenton Wallace. |
| 07/21/21 | Toronto Blue Jays traded RHP Joel Payamps to Kansas City Royals for cash. |
| 07/21/21 | Toronto Blue Jays signed LHP Ricky Tiedemann. |
| 07/21/21 | Toronto Blue Jays signed RHP Connor Cooke. |
| 07/21/21 | Toronto Blue Jays signed 3B Riley Tirotta. |
| 07/21/21 | Toronto Blue Jays signed RHP Matt Svanson. |
| 07/21/21 | Toronto Blue Jays signed RHP Irv Carter. |
| 07/21/21 | Toronto Blue Jays signed OF Jaden Rudd. |
| 07/20/21 | Toronto Blue Jays designated RHP T.J. Zeuch for assignment. |
| 07/20/21 | Toronto Blue Jays optioned C Alejandro Kirk to Buffalo Bisons. |
| 07/20/21 | Toronto Blue Jays optioned LHP Anthony Kay to Buffalo Bisons. |
| 07/19/21 | Toronto Blue Jays recalled CF Jonathan Davis from Buffalo Bisons. |
| 07/19/21 | Toronto Blue Jays recalled RHP Thomas Hatch from Buffalo Bisons. |
| 07/19/21 | Toronto Blue Jays optioned CF Jonathan Davis to Buffalo Bisons. |
| 07/19/21 | 2B Breyvic Valera roster status changed by Toronto Blue Jays. |
| 07/19/21 | Toronto Blue Jays placed RHP Alek Manoah on the 10-day injured list. Right back contusion. |
| 07/19/21 | Toronto Blue Jays placed RHP Anthony Castro on the 10-day injured list. Right ulnar nerve irritation. |
| 07/18/21 | Toronto Blue Jays designated LHP Nick Allgeyer for assignment. |
| 07/18/21 | Toronto Blue Jays sent RHP Tyler Chatwood on a rehab assignment to Buffalo Bisons. |
| 07/18/21 | Toronto Blue Jays selected the contract of 2B Breyvic Valera from Buffalo Bisons. |
| 07/16/21 | Toronto Blue Jays signed RHP Gunnar Hoglund. |
| 07/16/21 | Toronto Blue Jays activated LHP Ryan Borucki. |
| 07/16/21 | Toronto Blue Jays designated RHP Joel Payamps for assignment. |
| 07/08/21 | Cincinnati Reds traded OF Darlin Guzman to Toronto Blue Jays. |
| 07/07/21 | Toronto Blue Jays optioned RHP Trent Thornton to Buffalo Bisons. |
| 07/07/21 | Toronto Blue Jays sent LHP Ryan Borucki on a rehab assignment to Buffalo Bisons. |
| 07/07/21 | RHP Trevor Richards, and assigned to Toronto Blue Jays. |
| 07/06/21 | Toronto Blue Jays placed LHP Ryan Borucki on the 60-day injured list. Left forearm flexor strain. |
| 07/06/21 | Toronto Blue Jays traded 1B Rowdy Tellez to Milwaukee Brewers for RHP Bowden Francis and RHP Trevor Richards. |
| 07/06/21 | Toronto Blue Jays traded 1B Rowdy Tellez to Milwaukee Brewers for RHP Bowden Francis and RHP Trevor Richards. |
| 07/06/21 | Toronto Blue Jays optioned RHP Thomas Hatch to Buffalo Bisons. |
| 07/06/21 | Toronto Blue Jays traded 1B Rowdy Tellez to Milwaukee Brewers for RHP Bowden Francis and RHP Trevor Richards. |
| 07/04/21 | Toronto Blue Jays sent LHP Travis Bergen outright to Buffalo Bisons. |
| 07/04/21 | Toronto Blue Jays sent RHP Jeremy Beasley outright to Buffalo Bisons. |
| 07/04/21 | Toronto Blue Jays activated RHP Rafael Dolis. |
| 07/04/21 | Toronto Blue Jays optioned LHP Nick Allgeyer to Buffalo Bisons. |
| 07/03/21 | Toronto Blue Jays optioned C Riley Adams to Buffalo Bisons. |
| 07/03/21 | Toronto Blue Jays activated C Danny Jansen. |
| 07/02/21 | Toronto Blue Jays recalled LHP Nick Allgeyer from Buffalo Bisons. |
| 07/02/21 | Toronto Blue Jays sent RHP Rafael Dolis on a rehab assignment to Buffalo Bisons. |
| 07/02/21 | Toronto Blue Jays recalled RHP Anthony Castro from Buffalo Bisons. |
| 07/02/21 | Toronto Blue Jays optioned RHP Patrick Murphy to Buffalo Bisons. |
| 07/02/21 | Toronto Blue Jays placed RHP Tyler Chatwood on the 10-day injured list. Neck strain. |
| 07/02/21 | Toronto Blue Jays activated RHP Alek Manoah. |