Red Sox Roster & Staff
Transactions
| Date | Transaction |
| 11/30/21 | LF Tim Locastro elected free agency. |
| 11/29/21 | Boston Red Sox signed free agent RHP Wandy Abreu to a minor league contract. |
| 11/27/21 | Boston Red Sox activated RHP Michael Wacha. |
| 11/27/21 | Boston Red Sox activated RHP Michael Wacha. |
| 11/27/21 | Boston Red Sox signed free agent RHP Michael Wacha. |
| 11/19/21 | Boston Red Sox selected the contract of RHP Kutter Crawford from Worcester Red Sox. |
| 11/19/21 | Boston Red Sox selected the contract of RHP Brayan Bello from Portland Sea Dogs. |
| 11/19/21 | Boston Red Sox selected the contract of SS Jeter Downs from Worcester Red Sox. |
| 11/19/21 | Boston Red Sox selected the contract of RHP Josh Winckowski from Worcester Red Sox. |
| 11/18/21 | Boston Red Sox signed free agent OF Jose Liriano to a minor league contract. |
| 11/17/21 | Boston Red Sox signed free agent CF Michael Gettys to a minor league contract. |
| 11/12/21 | Boston Red Sox signed free agent RHP Cristian Nunez to a minor league contract. |
| 11/07/21 | LHP Martin Perez elected free agency. |
| 11/07/21 | RHP Garrett Richards elected free agency. |
| 11/05/21 | Boston Red Sox claimed LF Tim Locastro off waivers from New York Yankees. |
| 11/04/21 | LF Kyle Schwarber elected free agency. |
| 11/03/21 | RHP Hansel Robles elected free agency. |
| 11/03/21 | LHP Eduardo Rodriguez elected free agency. |
| 11/03/21 | SS Danny Santana elected free agency. |
| 11/03/21 | RHP Adam Ottavino elected free agency. |
| 11/03/21 | 3B Travis Shaw elected free agency. |