Giants Roster & Staff
Transactions
| Date | Transaction |
| 06/29/22 | San Francisco Giants activated CF LaMonte Wade Jr. from the 10-day injured list. |
| 06/29/22 | San Francisco Giants optioned C Yermin Mercedes to Sacramento River Cats. |
| 06/28/22 | San Francisco Giants sent LHP Jose Alvarez on a rehab assignment to Sacramento River Cats. |
| 06/26/22 | San Francisco Giants placed SS Brandon Crawford on the 10-day injured list retroactive to June 25, 2022. Left knee inflammation. |
| 06/26/22 | San Francisco Giants recalled C Yermin Mercedes from Sacramento River Cats. |
| 06/25/22 | Cincinnati Reds claimed C Michael Papierski off waivers from San Francisco Giants. |
| 06/24/22 | San Francisco Giants recalled RHP Yunior Marte from Sacramento River Cats. |
| 06/24/22 | San Francisco Giants optioned RHP Zack Littell to Sacramento River Cats. |
| 06/23/22 | San Francisco Giants placed OF Luis Gonzalez on the 10-day injured list retroactive to June 22, 2022. Low back strain. |
| 06/23/22 | San Francisco Giants recalled 2B Donovan Walton from Sacramento River Cats. |
| 06/21/22 | San Francisco Giants activated RHP Anthony DeSclafani. |
| 06/21/22 | San Francisco Giants transferred RHP Sam Delaplane from the 7-day injured list to the 60-day injured list. Right forearm strain. |
| 06/21/22 | San Francisco Giants placed LHP Jose Alvarez on the 15-day injured list. Lower back tightness. |
| 06/21/22 | San Francisco Giants recalled RHP Sam Delaplane from San Jose Giants. |
| 06/19/22 | San Francisco Giants activated RHP Alex Cobb from the 15-day injured list. |
| 06/19/22 | San Francisco Giants optioned RHP Mauricio Llovera to Sacramento River Cats. |
| 06/18/22 | San Francisco Giants sent CF LaMonte Wade Jr. on a rehab assignment to Sacramento River Cats. |
| 06/18/22 | San Francisco Giants designated C Michael Papierski for assignment. |
| 06/18/22 | San Francisco Giants optioned C Yermin Mercedes to Sacramento River Cats. |
| 06/18/22 | San Francisco Giants claimed C Yermin Mercedes off waivers from Chicago White Sox. |
| 06/17/22 | San Francisco Giants signed free agent LHP Matt Hall to a minor league contract. |
| 06/14/22 | San Francisco Giants activated 1B Brandon Belt from the 10-day injured list. |
| 06/14/22 | San Francisco Giants optioned 2B Donovan Walton to Sacramento River Cats. |
| 06/13/22 | San Francisco Giants optioned OF Heliot Ramos to Sacramento River Cats. |
| 06/13/22 | San Francisco Giants recalled OF Heliot Ramos and from Sacramento River Cats. |
| 06/13/22 | San Francisco Giants recalled RHP Mauricio Llovera from Sacramento River Cats. |
| 06/11/22 | San Francisco Giants placed RHP Jakob Junis on the 15-day injured list. Left hamstring strain. |
| 06/11/22 | San Francisco Giants sent RHP Anthony DeSclafani on a rehab assignment to Sacramento River Cats. |
| 06/11/22 | Cincinnati Reds claimed OF Stuart Fairchild and off waivers from San Francisco Giants. |
| 06/11/22 | Seattle Mariners claimed 3B Kevin Padlo off waivers from San Francisco Giants. |
| 06/09/22 | San Francisco Giants sent CF LaMonte Wade Jr. on a rehab assignment to Sacramento River Cats. |
| 06/08/22 | San Francisco Giants signed free agent RHP Ofelky Peralta to a minor league contract. |
| 06/08/22 | San Francisco Giants designated 3B Kevin Padlo for assignment. |
| 06/08/22 | San Francisco Giants signed free agent RHP Shelby Miller to a minor league contract. |
| 06/08/22 | San Francisco Giants optioned C Joey Bart to Sacramento River Cats. |
| 06/08/22 | San Francisco Giants selected the contract of C Austin Wynns from Sacramento River Cats. |
| 06/08/22 | San Francisco Giants traded LHP Michael Plassmeyer and cash to Philadelphia Phillies for C Austin Wynns. |
| 06/08/22 | San Francisco Giants traded LHP Michael Plassmeyer and cash to Philadelphia Phillies for C Austin Wynns. |
| 06/07/22 | San Francisco Giants placed RHP Alex Cobb on the 15-day injured list retroactive to June 4, 2022. Neck strain. |
| 06/07/22 | San Francisco Giants activated 1B Darin Ruf from the bereavement list. |
| 06/07/22 | San Francisco Giants recalled LHP Sam Long from Sacramento River Cats. |
| 06/06/22 | San Francisco Giants optioned 3B Jason Vosler to Sacramento River Cats. |
| 06/04/22 | San Francisco Giants activated LF Austin Slater from the 10-day injured list. |
| 06/04/22 | San Francisco Giants designated OF Stuart Fairchild for assignment. |
| 06/04/22 | San Francisco Giants optioned RHP Sean Hjelle to Sacramento River Cats. |
| 06/04/22 | San Francisco Giants optioned RHP Sam Delaplane to San Jose Giants. |
| 06/04/22 | San Francisco Giants selected the contract of RHP Sam Delaplane from Sacramento River Cats. |
| 06/03/22 | San Francisco Giants optioned LHP Sam Long to Sacramento River Cats. |
| 06/03/22 | San Francisco Giants recalled RHP Sean Hjelle from Sacramento River Cats. |
| 06/02/22 | San Francisco Giants sent CF Steven Duggar on a rehab assignment to Sacramento River Cats. |
| 06/01/22 | San Francisco Giants optioned OF Stuart Fairchild to Sacramento River Cats. |
| 06/01/22 | San Francisco Giants optioned OF Heliot Ramos to Sacramento River Cats. |
| 06/01/22 | San Francisco Giants optioned OF Heliot Ramos to Sacramento River Cats. |
| 06/01/22 | San Francisco Giants recalled LHP Sam Long from Sacramento River Cats. |
| 06/01/22 | San Francisco Giants recalled 3B Jason Vosler from Sacramento River Cats. |