Cubs Roster & Staff
Transactions
| Date | Transaction |
| 05/30/23 | Chicago Cubs optioned RHP Michael Rucker to Iowa Cubs. |
| 05/30/23 | Chicago Cubs recalled RHP Hayden Wesneski from Iowa Cubs. |
| 05/25/23 | Chicago Cubs released 1B Eric Hosmer. |
| 05/25/23 | Chicago Cubs activated RHP Kyle Hendricks from the 15-day injured list. |
| 05/25/23 | Chicago Cubs optioned 2B Nick Madrigal to Iowa Cubs. |
| 05/24/23 | Chicago Cubs placed RHP Nick Burdi on the 15-day injured list retroactive to May 21, 2023. Appendicitis. |
| 05/24/23 | Chicago Cubs recalled RHP Javier Assad from Iowa Cubs. |
| 05/19/23 | Chicago Cubs placed 1B Cody Bellinger on the 10-day injured list. Left knee contusion. |
| 05/19/23 | Chicago Cubs activated 2B Nico Hoerner from the 10-day injured list. |
| 05/19/23 | Chicago Cubs designated 1B Eric Hosmer for assignment. |
| 05/19/23 | Chicago Cubs recalled 3B Edwin Ríos from Iowa Cubs. |
| 05/19/23 | Chicago Cubs selected the contract of LF Mike Tauchman from Iowa Cubs. |
| 05/19/23 | Chicago Cubs optioned RHP Keegan Thompson to Iowa Cubs. |
| 05/15/23 | Chicago Cubs placed RHP Brad Boxberger on the 15-day injured list retroactive to May 14, 2023. Right forearm strain. |
| 05/15/23 | Chicago Cubs transferred RHP Adrian Sampson from the 7-day injured list to the 60-day injured list. |
| 05/15/23 | Chicago Cubs recalled RHP Jeremiah Estrada from Iowa Cubs. |
| 05/15/23 | Chicago Cubs selected the contract of RHP Nick Burdi from Iowa Cubs. |
| 05/15/23 | Chicago Cubs optioned RHP Hayden Wesneski to Iowa Cubs. |
| 05/14/23 | Chicago Cubs transferred RHP Brad Boxberger from the 15-day injured list to the 60-day injured list. |
| 05/12/23 | Chicago Cubs activated LHP Brandon Hughes from the 15-day injured list. |
| 05/12/23 | Chicago Cubs placed 2B Nico Hoerner on the 10-day injured list retroactive to May 9, 2023. Left hamstring strain. |
| 05/12/23 | Chicago Cubs recalled 2B Miles Mastrobuoni from Iowa Cubs. |
| 05/12/23 | Chicago Cubs optioned RHP Javier Assad to Iowa Cubs. |
| 05/10/23 | Chicago Cubs activated C Yan Gomes from the 7-day injured list. |
| 05/10/23 | Chicago Cubs optioned C Miguel Amaya to Iowa Cubs. |
| 05/08/23 | Chicago Cubs optioned OF Nelson Velázquez to Iowa Cubs. |
| 05/08/23 | Chicago Cubs recalled SS Christopher Morel from Iowa Cubs. |
| 05/06/23 | Chicago Cubs sent RHP Codi Heuer on a rehab assignment to Iowa Cubs. |
| 05/05/23 | Chicago Cubs optioned 3B Edwin Ríos to Iowa Cubs. |
| 05/05/23 | Chicago Cubs sent LHP Ryan Borucki outright to Iowa Cubs. |
| 05/05/23 | Chicago Cubs selected the contract of 1B Matt Mervis from Iowa Cubs. |
| 05/04/23 | Chicago Cubs activated RHP Jameson Taillon from the 15-day injured list. |
| 05/04/23 | Chicago Cubs optioned RHP Jeremiah Estrada to Iowa Cubs. |
| 05/03/23 | Chicago Cubs placed C Yan Gomes on the 7-day injured list retroactive to May 2, 2023. Concussion. |
| 05/03/23 | Chicago Cubs traded C Luis Torrens to Baltimore Orioles for cash. |
| 05/03/23 | Chicago Cubs recalled RHP Javier Assad from Iowa Cubs. |
| 05/02/23 | Chicago Cubs designated LHP Ryan Borucki for assignment. |
| 05/02/23 | Chicago Cubs recalled C Miguel Amaya from Tennessee Smokies. |
| 05/01/23 | Chicago Cubs signed free agent RHP Nestor Pirela to a minor league contract. |