Cubs Roster & Staff
Transactions
| Date | Transaction |
| 04/16/26 | RHP Daniel Palencia changed number to 48. |
| 04/16/26 | 3B Matt Shaw changed number to 6. |
| 04/16/26 | LHP Ryan Rolison changed number to 33. |
| 04/16/26 | LHP Hoby Milner changed number to 41. |
| 04/16/26 | RHP Colin Rea changed number to 53. |
| 04/16/26 | LHP Riley Martin changed number to 51. |
| 04/16/26 | C Carson Kelly changed number to 15. |
| 04/16/26 | LHP Luke Little changed number to 43. |
| 04/16/26 | 2B Scott Kingery changed number to 12. |
| 04/16/26 | CF Pete Crow-Armstrong changed number to 4. |
| 04/16/26 | LF Michael Conforto changed number to 20. |
| 04/16/26 | LHP Shota Imanaga changed number to 18. |
| 04/16/26 | LF Ian Happ changed number to 8. |
| 04/16/26 | 2B Nico Hoerner changed number to 2. |
| 04/16/26 | 1B Michael Busch changed number to 29. |
| 04/16/26 | RHP Edward Cabrera changed number to 30. |
| 04/16/26 | RHP Ben Brown changed number to 32. |
| 04/16/26 | SS Dansby Swanson changed number to 7. |
| 04/16/26 | C Miguel Amaya changed number to 9. |
| 04/16/26 | C Moisés Ballesteros changed number to 25. |
| 04/16/26 | RHP Javier Assad changed number to 72. |
| 04/16/26 | LHP Caleb Thielbar changed number to 24. |
| 04/16/26 | RHP Jameson Taillon changed number to 50. |
| 04/16/26 | 3B Alex Bregman changed number to 3. |
| 04/16/26 | RF Seiya Suzuki changed number to 27. |
| 04/16/26 | RHP Jacob Webb changed number to 71. |
| 04/15/26 | C Miguel Amaya changed number to 42. |
| 04/15/26 | LF Ian Happ changed number to 42. |
| 04/15/26 | LF Michael Conforto changed number to 42. |
| 04/15/26 | LHP Ryan Rolison changed number to 42. |
| 04/15/26 | SS Dansby Swanson changed number to 42. |
| 04/15/26 | RHP Ben Brown changed number to 42. |
| 04/15/26 | RHP Edward Cabrera changed number to 42. |
| 04/15/26 | 1B Michael Busch changed number to 42. |
| 04/15/26 | RHP Daniel Palencia changed number to 42. |
| 04/15/26 | 2B Scott Kingery changed number to 42. |
| 04/15/26 | LHP Riley Martin changed number to 42. |
| 04/15/26 | CF Pete Crow-Armstrong changed number to 42. |
| 04/15/26 | C Carson Kelly changed number to 42. |
| 04/15/26 | C Moisés Ballesteros changed number to 42. |
| 04/15/26 | 2B Nico Hoerner changed number to 42. |
| 04/15/26 | RHP Jameson Taillon changed number to 42. |
| 04/15/26 | LHP Caleb Thielbar changed number to 42. |
| 04/15/26 | LHP Shota Imanaga changed number to 42. |
| 04/15/26 | RF Seiya Suzuki changed number to 42. |
| 04/15/26 | LHP Hoby Milner changed number to 42. |
| 04/15/26 | RHP Javier Assad changed number to 42. |
| 04/15/26 | RHP Jacob Webb changed number to 42. |
| 04/15/26 | LHP Luke Little changed number to 42. |
| 04/15/26 | 3B Matt Shaw changed number to 42. |
| 04/15/26 | 3B Alex Bregman changed number to 42. |
| 04/15/26 | RHP Colin Rea changed number to 42. |
| 04/14/26 | Chicago Cubs placed RHP Ethan Roberts on the 15-day injured list retroactive to April 13, 2026. Right middle finger laceration. |
| 04/14/26 | Chicago Cubs signed free agent RHP Paul Campbell to a minor league contract. |
| 04/14/26 | Chicago Cubs recalled LHP Ryan Rolison from Iowa Cubs. |
| 04/14/26 | Chicago Cubs recalled LHP Luke Little from Iowa Cubs. |
| 04/14/26 | Chicago Cubs optioned LHP Charlie Barnes to Iowa Cubs. |
| 04/13/26 | Chicago Cubs signed free agent OF Stharling De Los Santos to a minor league contract. |
| 04/13/26 | Chicago Cubs signed free agent SS Stharling De Los Santos to a minor league contract. |
| 04/12/26 | Chicago Cubs placed RHP Hunter Harvey on the 15-day injured list retroactive to April 9, 2026. Right triceps inflammation. |
| 04/12/26 | Chicago Cubs sent LF Dylan Carlson outright to Iowa Cubs. |
| 04/12/26 | Chicago Cubs selected the contract of LHP Charlie Barnes from Iowa Cubs. |
| 04/10/26 | Chicago Cubs placed RHP Phil Maton on the 15-day injured list retroactive to April 8, 2026. Right knee tendinitis. |
| 04/10/26 | Chicago Cubs activated RF Seiya Suzuki from the 10-day injured list. |
| 04/10/26 | Chicago Cubs designated LF Dylan Carlson for assignment. |
| 04/10/26 | Chicago Cubs recalled RHP Ethan Roberts from Iowa Cubs. |
| 04/07/26 | Chicago Cubs signed free agent RHP Tyler Beede to a minor league contract. |
| 04/06/26 | Chicago Cubs placed LHP Matthew Boyd on the 15-day injured list retroactive to April 3, 2026. Left biceps strain. |
| 04/06/26 | Chicago Cubs recalled RHP Javier Assad from Iowa Cubs. |
| 04/06/26 | RHP Ethan Roberts returned to Iowa Cubs from Chicago Cubs. |
| 04/05/26 | Chicago Cubs placed RHP Cade Horton on the 15-day injured list retroactive to April 4, 2026. Right forearm strain. |
| 04/05/26 | Chicago Cubs recalled LHP Riley Martin from Iowa Cubs. |
| 04/05/26 | Chicago Cubs recalled RHP Ethan Roberts from Iowa Cubs. |
| 04/03/26 | Chicago Cubs sent RF Seiya Suzuki on a rehab assignment to Knoxville Smokies. |
| 04/03/26 | Chicago Cubs sent RF Seiya Suzuki on a rehab assignment to Knoxville Smokies. |
| 04/02/26 | Chicago Cubs signed free agent RHP Naikys Piedra to a minor league contract. |