Cubs Roster & Staff
Transactions
| Date | Transaction |
| 11/18/22 | LF Rafael Ortega elected free agency. |
| 11/18/22 | LHP Brailyn Marquez elected free agency. |
| 11/18/22 | RHP Alexander Vizcaino elected free agency. |
| 11/18/22 | Chicago Cubs claimed 3B Rylan Bannon off waivers from Atlanta Braves. |
| 11/15/22 | Chicago Cubs selected the contract of OF Brennen Davis from Iowa Cubs. |
| 11/15/22 | Chicago Cubs selected the contract of RHP Ryan Jensen from Tennessee Smokies. |
| 11/15/22 | Chicago Cubs selected the contract of CF Kevin Alcantara from Myrtle Beach Pelicans. |
| 11/15/22 | Chicago Cubs selected the contract of RHP Ben Brown from Tennessee Smokies. |
| 11/15/22 | Tampa Bay Rays traded 2B Miles Mastrobuoni to Chicago Cubs for RHP Alfredo Zarraga. |
| 11/15/22 | Tampa Bay Rays traded 2B Miles Mastrobuoni to Chicago Cubs for RHP Alfredo Zarraga. |
| 11/14/22 | Chicago Cubs released RF Jason Heyward. |
| 11/11/22 | Chicago Cubs sent 3B Esteban Quiroz outright to Iowa Cubs. |
| 11/11/22 | Chicago Cubs sent 2B Jared Young outright to Iowa Cubs. |
| 11/10/22 | 3B Esteban Quiroz roster status changed by Chicago Cubs. |
| 11/10/22 | Chicago Cubs activated RHP Codi Heuer from the 60-day injured list. |
| 11/10/22 | Chicago Cubs activated RHP Ethan Roberts from the 60-day injured list. |
| 11/10/22 | Chicago Cubs activated LF Rafael Ortega from the 60-day injured list. |
| 11/10/22 | 2B Jared Young roster status changed by Chicago Cubs. |
| 11/10/22 | Chicago Cubs activated RF Jason Heyward from the 60-day injured list. |
| 11/10/22 | Chicago Cubs activated RHP Kyle Hendricks from the 60-day injured list. |
| 11/10/22 | Chicago Cubs sent CF Narciso Crook outright to Iowa Cubs. |
| 11/10/22 | Chicago Cubs sent RHP Anderson Espinoza outright to Iowa Cubs. |
| 11/10/22 | Chicago Cubs sent 2B David Bote outright to Iowa Cubs. |
| 11/10/22 | Chicago Cubs sent RF Franmil Reyes outright to Iowa Cubs. |
| 11/10/22 | Chicago Cubs sent LHP Steven Brault outright to Iowa Cubs. |
| 11/10/22 | Chicago Cubs sent RHP Alec Mills outright to Iowa Cubs. |
| 11/10/22 | Chicago Cubs sent LHP Brad Wieck outright to Iowa Cubs. |
| 11/09/22 | LHP Drew Smyly elected free agency. |
| 11/09/22 | 2B David Bote roster status changed by Chicago Cubs. |
| 11/06/22 | C Willson Contreras elected free agency. |
| 11/06/22 | LHP Wade Miley elected free agency. |