Cubs Roster & Staff
Transactions
| Date | Transaction |
| 01/31/22 | Chicago Cubs signed free agent C John Hicks to a minor league contract. |
| 01/24/22 | Chicago Cubs signed free agent RHP Eric Yardley to a minor league contract. |
| 01/18/22 | Chicago Cubs signed free agent C Abel De Leon to a minor league contract. |
| 01/17/22 | Chicago Cubs signed free agent OF Daniel Benschop to a minor league contract. |
| 01/17/22 | Chicago Cubs signed free agent C Adan Sanchez to a minor league contract. |
| 01/15/22 | Chicago Cubs signed free agent OF Josias Ramirez to a minor league contract. |
| 01/15/22 | Chicago Cubs signed free agent OF Josefrailin Alcantara to a minor league contract. |
| 01/15/22 | Chicago Cubs signed free agent RHP Freilyn Silverio to a minor league contract. |
| 01/15/22 | Chicago Cubs signed free agent SS Sandy Sanchez to a minor league contract. |
| 01/15/22 | Chicago Cubs signed free agent OF Albert Belliard to a minor league contract. |
| 01/15/22 | Chicago Cubs signed free agent SS Alexis Hernandez to a minor league contract. |
| 01/15/22 | C Yidel Diaz assigned to Chicago Cubs. |
| 01/15/22 | Chicago Cubs signed free agent SS Moises Febrillet to a minor league contract. |
| 01/15/22 | Chicago Cubs signed free agent SS Jefferson Rojas to a minor league contract. |
| 01/15/22 | Chicago Cubs signed free agent 2B Darlyn De Leon to a minor league contract. |