Cubs Roster & Staff
Transactions
| Date | Transaction |
| 07/31/21 | Chicago Cubs activated RHP Codi Heuer. |
| 07/30/21 | Chicago Cubs selected the contract of SS Andrew Romine from Iowa Cubs. |
| 07/30/21 | Chicago Cubs recalled CF Johneshwy Fargas from Iowa Cubs. |
| 07/30/21 | Chicago Cubs traded 3B Kris Bryant to San Francisco Giants for LF Alexander Canario and RHP Caleb Kilian. |
| 07/30/21 | Chicago Cubs traded 3B Kris Bryant to San Francisco Giants for LF Alexander Canario and RHP Caleb Kilian. |
| 07/30/21 | Chicago Cubs selected the contract of RHP Michael Rucker, and from Iowa Cubs. |
| 07/30/21 | Chicago Cubs recalled 1B Frank Schwindel, and from Iowa Cubs. |
| 07/30/21 | Chicago Cubs signed free agent RHP Walker Powell to a minor league contract. |
| 07/30/21 | Chicago Cubs traded 3B Kris Bryant to San Francisco Giants for LF Alexander Canario and RHP Caleb Kilian. |
| 07/30/21 | Chicago Cubs traded SS Javier Baez, RHP Trevor Williams and cash to New York Mets for OF Pete Crow-Armstrong. |
| 07/30/21 | Chicago Cubs traded SS Javier Baez, RHP Trevor Williams and cash to New York Mets for OF Pete Crow-Armstrong. |
| 07/30/21 | Chicago Cubs recalled RHP Manuel Rodriguez from Iowa Cubs. |
| 07/30/21 | Chicago Cubs traded SS Javier Baez, RHP Trevor Williams and cash to New York Mets for OF Pete Crow-Armstrong. |
| 07/30/21 | San Diego Padres traded RHP Anderson Espinoza to Chicago Cubs for CF Jake Marisnick. |
| 07/30/21 | Chicago Cubs traded RHP Craig Kimbrel to Chicago White Sox for 2B Nick Madrigal and RHP Codi Heuer. |
| 07/30/21 | San Diego Padres traded RHP Anderson Espinoza to Chicago Cubs for CF Jake Marisnick. |
| 07/30/21 | Chicago Cubs traded RHP Craig Kimbrel to Chicago White Sox for 2B Nick Madrigal and RHP Codi Heuer. |
| 07/30/21 | Chicago Cubs traded RHP Craig Kimbrel to Chicago White Sox for 2B Nick Madrigal and RHP Codi Heuer. |
| 07/30/21 | Chicago Cubs activated RHP Jake Arrieta from the 10-day injured list. |
| 07/29/21 | Chicago Cubs placed 2B Nico Hoerner on the 10-day injured list. Right oblique strain. |
| 07/29/21 | Chicago Cubs selected the contract of RHP Jake Jewell from Iowa Cubs. |
| 07/29/21 | Chicago Cubs traded RHP Ryan Tepera to Chicago White Sox for LHP Bailey Horn. |
| 07/29/21 | Chicago Cubs traded RHP Ryan Tepera to Chicago White Sox for LHP Bailey Horn. |
| 07/29/21 | Chicago Cubs optioned RHP Alexander Vizcaino to South Bend Cubs. |
| 07/29/21 | Chicago Cubs recalled SS Sergio Alcantara from Iowa Cubs. |
| 07/29/21 | Chicago Cubs placed RHP Kohl Stewart on the 60-day injured list. Right elbow inflammation. |
| 07/29/21 | Chicago Cubs recalled RHP Trevor Megill from Iowa Cubs. |
| 07/29/21 | New York Yankees traded RHP Alexander Vizcaino and CF Kevin Alcantara to Chicago Cubs for 1B Anthony Rizzo and cash. |
| 07/29/21 | New York Yankees traded RHP Alexander Vizcaino and CF Kevin Alcantara to Chicago Cubs for 1B Anthony Rizzo and cash. |
| 07/29/21 | New York Yankees traded RHP Alexander Vizcaino and CF Kevin Alcantara to Chicago Cubs for 1B Anthony Rizzo and cash. |
| 07/29/21 | Chicago Cubs placed RHP Dillon Maples on the 10-day injured list. Blister. |
| 07/29/21 | Chicago Cubs signed LHP Wilson Cunningham. |
| 07/29/21 | Chicago Cubs optioned RHP Cory Abbott to Iowa Cubs. |
| 07/28/21 | Chicago Cubs sent RHP Rowan Wick on a rehab assignment to Iowa Cubs. |
| 07/28/21 | Chicago Cubs released 2B Eric Sogard. |
| 07/27/21 | Chicago Cubs optioned RHP Keegan Thompson to Iowa Cubs. |
| 07/27/21 | Chicago Cubs recalled RHP Cory Abbott from Iowa Cubs. |
| 07/27/21 | Chicago Cubs recalled LHP Kyle Ryan from Iowa Cubs. |
| 07/26/21 | Chicago Cubs signed free agent C Jairo Diaz to a minor league contract. |
| 07/26/21 | Chicago Cubs traded LHP Andrew Chafin to Oakland Athletics for 1B Greg Deichmann and RHP Daniel Palencia. |
| 07/26/21 | Chicago Cubs signed free agent RHP Yenrri Rojas to a minor league contract. |
| 07/26/21 | Chicago Cubs traded LHP Andrew Chafin to Oakland Athletics for 1B Greg Deichmann and RHP Daniel Palencia. |
| 07/26/21 | Chicago Cubs sent C Austin Romine on a rehab assignment to ACL Cubs. |
| 07/26/21 | Chicago Cubs traded LHP Andrew Chafin to Oakland Athletics for 1B Greg Deichmann and RHP Daniel Palencia. |
| 07/25/21 | Chicago Cubs optioned RHP Trevor Megill to Iowa Cubs. |
| 07/25/21 | Chicago Cubs activated 2B David Bote. |
| 07/24/21 | Chicago Cubs signed 3B James Triantos. |
| 07/24/21 | Chicago Cubs signed RHP Erian Rodriguez. |
| 07/24/21 | Chicago Cubs signed SS Christian Olivo. |
| 07/24/21 | Chicago Cubs signed RHP Frankie Scalzo Jr.. |
| 07/24/21 | Chicago Cubs signed 3B BJ Murray Jr.. |
| 07/24/21 | Chicago Cubs signed RHP Zachary Leigh. |
| 07/23/21 | Chicago Cubs designated 2B Eric Sogard for assignment. |
| 07/23/21 | Chicago Cubs placed LHP Brad Wieck on the 60-day injured list. Irregular heartbeat. |
| 07/23/21 | Chicago Cubs claimed CF Johneshwy Fargas off waivers from New York Mets. |
| 07/23/21 | Chicago Cubs optioned CF Johneshwy Fargas to Iowa Cubs. |
| 07/23/21 | Chicago Cubs activated 3B Matt Duffy. |
| 07/22/21 | Chicago Cubs recalled RHP Trevor Megill from Iowa Cubs. |
| 07/22/21 | Chicago Cubs optioned SS Sergio Alcantara to Iowa Cubs. |
| 07/21/21 | Chicago Cubs signed free agent RHP Tyler Santana to a minor league contract. |
| 07/19/21 | Chicago Cubs activated RHP Dillon Maples. |
| 07/19/21 | Chicago Cubs optioned LHP Kyle Ryan to Iowa Cubs. |
| 07/18/21 | Chicago Cubs claimed 1B Frank Schwindel off waivers from Oakland Athletics. |
| 07/17/21 | Chicago Cubs sent 2B David Bote on a rehab assignment to Iowa Cubs. |
| 07/17/21 | Chicago Cubs sent RHP Rowan Wick on a rehab assignment to South Bend Cubs. |
| 07/17/21 | Chicago Cubs signed RHP Dominic Hambley. |
| 07/16/21 | Chicago Cubs signed OF Parker Chavers. |
| 07/16/21 | Chicago Cubs signed C Casey Opitz. |
| 07/16/21 | Chicago Cubs signed OF Peter Matt. |
| 07/16/21 | Chicago Cubs signed LHP Chase Watkins. |
| 07/16/21 | Chicago Cubs signed LHP Drew Gray. |
| 07/16/21 | Chicago Cubs signed LHP Jordan Wicks. |
| 07/16/21 | Chicago Cubs signed SS Liam Spence. |
| 07/16/21 | Chicago Cubs activated 2B Eric Sogard from the 10-day injured list. |
| 07/15/21 | Chicago Cubs signed OF Christian Franklin. |
| 07/15/21 | Chicago Cubs signed LHP Riley Martin. |
| 07/15/21 | Chicago Cubs traded CF Joc Pederson to Atlanta Braves for 1B Bryce Ball. |
| 07/15/21 | Chicago Cubs traded CF Joc Pederson to Atlanta Braves for 1B Bryce Ball. |
| 07/13/21 | Chicago Cubs sent 3B Matt Duffy on a rehab assignment to Iowa Cubs. |
| 07/12/21 | Chicago Cubs signed free agent RHP Jason Adam to a minor league contract. |
| 07/09/21 | Chicago Cubs activated RHP Ryan Tepera from the 10-day injured list. |
| 07/09/21 | Chicago Cubs optioned RHP Cory Abbott to Iowa Cubs. |
| 07/09/21 | Chicago Cubs placed LHP Brad Wieck on the 10-day injured list. Irregular heartbeat. |
| 07/09/21 | Chicago Cubs recalled LHP Kyle Ryan from Iowa Cubs. |
| 07/09/21 | Chicago Cubs signed free agent C Dean Nevarez to a minor league contract. |
| 07/08/21 | Chicago Cubs optioned LHP Justin Steele to Iowa Cubs. |
| 07/08/21 | Chicago Cubs sent C Taylor Gushue outright to Iowa Cubs. |
| 07/07/21 | Chicago Cubs placed RHP Jake Arrieta on the 10-day injured list. Right hamstring tightness. |
| 07/07/21 | Chicago Cubs recalled RHP Cory Abbott from Iowa Cubs. |
| 07/06/21 | Chicago Cubs activated RHP Trevor Williams. |
| 07/06/21 | Chicago Cubs placed 2B Eric Sogard on the 10-day injured list. Left thumb contusion. |
| 07/06/21 | Chicago Cubs placed RHP Kohl Stewart on the 10-day injured list. Right elbow inflammation. |
| 07/06/21 | Chicago Cubs recalled SS Sergio Alcantara from Iowa Cubs. |
| 07/05/21 | Chicago Cubs signed free agent C Robinson Chirinos. |
| 07/05/21 | Chicago Cubs designated C Taylor Gushue for assignment. |
| 07/04/21 | Chicago Cubs optioned SS Sergio Alcantara to Iowa Cubs. |
| 07/04/21 | Chicago Cubs activated 2B Nico Hoerner. |
| 07/03/21 | Chicago Cubs selected the contract of LHP Tony Cingrani from Lexington Legends. |
| 07/02/21 | Chicago Cubs recalled RHP Kohl Stewart from Iowa Cubs. |
| 07/01/21 | Chicago Cubs optioned RHP Tommy Nance to Iowa Cubs. |