Cardinals Roster & Staff
Transactions
| Date | Transaction |
| 03/25/25 | RHP Sean Harney roster status changed by St. Louis Cardinals. |
| 03/25/25 | New York Mets traded RHP Sean Harney to St. Louis Cardinals. |
| 03/24/25 | 3B Kleininger Teran assigned to St. Louis Cardinals. |
| 03/24/25 | St. Louis Cardinals placed LHP Zack Thompson on the 15-day injured list. |
| 03/23/25 | RHP Jose Davila assigned to St. Louis Cardinals. |
| 03/23/25 | 3B Cade McGee assigned to St. Louis Cardinals. |
| 03/23/25 | St. Louis Cardinals optioned RHP Michael McGreevy to Memphis Redbirds. |
| 03/23/25 | St. Louis Cardinals optioned 2B José Fermín to Memphis Redbirds. |
| 03/22/25 | 3B Trey Paige assigned to St. Louis Cardinals. |
| 03/22/25 | OF Bryce Madron assigned to St. Louis Cardinals. |
| 03/19/25 | St. Louis Cardinals released C Chance Sisco. |
| 03/19/25 | 2B Christian Martin assigned to St. Louis Cardinals. |
| 03/18/25 | C Ryan Campos assigned to St. Louis Cardinals. |
| 03/17/25 | 2B Ramon Mendoza assigned to St. Louis Cardinals. |
| 03/16/25 | St. Louis Cardinals optioned 2B Thomas Saggese to Memphis Redbirds. |
| 03/16/25 | St. Louis Cardinals optioned CF Michael Helman to Memphis Redbirds. |
| 03/16/25 | St. Louis Cardinals optioned LF Matt Koperniak to Memphis Redbirds. |
| 03/15/25 | RHP Jawilme Ramirez assigned to St. Louis Cardinals. |
| 03/15/25 | RHP Angel Gonzalez assigned to St. Louis Cardinals. |
| 03/15/25 | St. Louis Cardinals optioned RHP Riley O'Brien to Memphis Redbirds. |
| 03/15/25 | St. Louis Cardinals optioned RHP Roddery Muñoz to Memphis Redbirds. |
| 03/14/25 | LF Miguel Ugueto assigned to St. Louis Cardinals. |
| 03/14/25 | 3B Matt Lloyd assigned to St. Louis Cardinals. |
| 03/14/25 | 2B Tre Richardson assigned to St. Louis Cardinals. |
| 03/14/25 | RHP Benjamin Arias assigned to St. Louis Cardinals. |
| 03/14/25 | LHP Nathanael Heredia assigned to St. Louis Cardinals. |
| 03/13/25 | St. Louis Cardinals signed free agent RHP Phil Maton. |
| 03/13/25 | St. Louis Cardinals designated LHP Bailey Horn for assignment. |
| 03/13/25 | St. Louis Cardinals optioned RHP Gordon Graceffo to Memphis Redbirds. |
| 03/13/25 | St. Louis Cardinals traded LHP Bailey Horn to Detroit Tigers. |
| 03/13/25 | St. Louis Cardinals optioned RHP Ryan Loutos to Memphis Redbirds. |
| 03/12/25 | St. Louis Cardinals optioned RHP Tekoah Roby to Memphis Redbirds. |
| 03/11/25 | 3B Deniel Ortiz assigned to St. Louis Cardinals. |
| 03/11/25 | RHP Dionys Rodriguez assigned to St. Louis Cardinals. |
| 03/11/25 | RF Darlin Moquete assigned to St. Louis Cardinals. |
| 03/10/25 | CF Mike Antico assigned to St. Louis Cardinals. |
| 03/10/25 | RHP Hunter Hayes assigned to St. Louis Cardinals. |
| 03/10/25 | St. Louis Cardinals invited non-roster C Yohel Pozo to spring training. |
| 03/10/25 | LHP Michael Watson assigned to St. Louis Cardinals. |
| 03/10/25 | 2B Brody Moore assigned to St. Louis Cardinals. |
| 03/10/25 | 3B Jacob Buchberger assigned to St. Louis Cardinals. |
| 03/10/25 | RHP Tanner Jacobson assigned to St. Louis Cardinals. |
| 03/10/25 | RF Chris Rotondo assigned to St. Louis Cardinals. |
| 03/08/25 | RHP Sam Brodersen assigned to St. Louis Cardinals. |
| 03/08/25 | LHP Yordy Herrera assigned to St. Louis Cardinals. |
| 03/08/25 | RHP Mason Burns assigned to St. Louis Cardinals. |
| 03/08/25 | St. Louis Cardinals optioned RHP Sem Robberse to Memphis Redbirds. |
| 03/08/25 | St. Louis Cardinals optioned RHP Matt Svanson to Memphis Redbirds. |
| 03/07/25 | St. Louis Cardinals signed free agent LHP Hendrick Cana to a minor league contract. |
| 03/07/25 | RHP Nelfy Ynfante assigned to St. Louis Cardinals. |
| 03/07/25 | RHP Austin Love assigned to St. Louis Cardinals. |
| 03/07/25 | RHP Hunter Kublick assigned to St. Louis Cardinals. |
| 03/07/25 | St. Louis Cardinals optioned RHP Tink Hence to Memphis Redbirds. |
| 03/06/25 | St. Louis Cardinals reassigned RHP Sem Robberse to the minor leagues. |
| 03/05/25 | RHP Zane Mills assigned to St. Louis Cardinals. |
| 03/04/25 | LHP Nick Raquet assigned to St. Louis Cardinals. |
| 03/04/25 | RF Jose Suarez assigned to St. Louis Cardinals. |
| 03/04/25 | RHP Andrew Marrero assigned to St. Louis Cardinals. |
| 03/04/25 | C Graysen Tarlow roster status changed by St. Louis Cardinals. |
| 03/04/25 | C Graysen Tarlow assigned to St. Louis Cardinals. |
| 03/04/25 | C Chase Adkison assigned to St. Louis Cardinals. |
| 03/04/25 | C Josh Kross assigned to St. Louis Cardinals. |
| 03/04/25 | 2B Miguel Villarroel assigned to St. Louis Cardinals. |
| 03/04/25 | 3B Johnfrank Salazar assigned to St. Louis Cardinals. |
| 03/04/25 | C Heriberto Caraballo assigned to St. Louis Cardinals. |
| 03/04/25 | St. Louis Cardinals optioned LHP Bailey Horn to Memphis Redbirds. |
| 03/02/25 | OF Ian Petrutz assigned to St. Louis Cardinals. |
| 03/02/25 | OF Ian Petrutz roster status changed by St. Louis Cardinals. |
| 03/02/25 | St. Louis Cardinals reassigned LHP Bailey Horn to the minor leagues. |
| 03/02/25 | RHP Inohan Paniagua assigned to St. Louis Cardinals. |
| 03/02/25 | St. Louis Cardinals optioned LHP Bailey Horn to Memphis Redbirds. |
| 03/01/25 | CF Luis Pino assigned to St. Louis Cardinals. |