Rays Roster & Staff
Transactions
| Date | Transaction |
| 09/30/22 | Tampa Bay Rays signed free agent RHP Yordi Mateo to a minor league contract. |
| 09/30/22 | Tampa Bay Rays signed free agent RHP Yannelbinson Lugo to a minor league contract. |
| 09/29/22 | Tampa Bay Rays designated RHP Cristofer Ogando for assignment. |
| 09/29/22 | Tampa Bay Rays optioned RHP Calvin Faucher to Durham Bulls. |
| 09/29/22 | Tampa Bay Rays selected the contract of RHP Easton McGee from Durham Bulls. |
| 09/28/22 | Tampa Bay Rays activated RHP Tyler Glasnow from the 60-day injured list. |
| 09/28/22 | Tampa Bay Rays transferred 2B Brandon Lowe from the 10-day injured list to the 60-day injured list. Low back discomfort. |
| 09/28/22 | Tampa Bay Rays optioned RHP Cristofer Ogando to Durham Bulls. |
| 09/27/22 | Tampa Bay Rays sent CF Roman Quinn on a rehab assignment to Durham Bulls. |
| 09/25/22 | Tampa Bay Rays sent RHP Dusten Knight outright to Durham Bulls. |
| 09/24/22 | Tampa Bay Rays sent RHP Kevin Herget outright to Durham Bulls. |
| 09/23/22 | Tampa Bay Rays placed LHP Ryan Yarbrough on the 15-day injured list. Right oblique strain. |
| 09/23/22 | Tampa Bay Rays designated RHP Dusten Knight for assignment. |
| 09/23/22 | Tampa Bay Rays activated RHP Cristofer Ogando. |
| 09/23/22 | Tampa Bay Rays recalled RHP Calvin Faucher from Durham Bulls. |
| 09/23/22 | Tampa Bay Rays selected the contract of RHP Cristofer Ogando from Durham Bulls. |
| 09/22/22 | Tampa Bay Rays designated RHP Kevin Herget for assignment. |
| 09/22/22 | Tampa Bay Rays optioned C Rene Pinto to Durham Bulls. |
| 09/22/22 | Tampa Bay Rays selected the contract of 2B Miles Mastrobuoni from Durham Bulls. |
| 09/21/22 | Tampa Bay Rays placed LHP Jalen Beeks on the 15-day injured list retroactive to September 18, 2022. Right lower leg tightness. |
| 09/21/22 | Tampa Bay Rays placed RHP Nick Anderson on the 60-day injured list. plantar fasciitis. |
| 09/21/22 | Tampa Bay Rays selected the contract of RHP Dusten Knight from Durham Bulls. |
| 09/21/22 | Tampa Bay Rays recalled RHP Nick Anderson from Durham Bulls. |
| 09/16/22 | Tampa Bay Rays transferred RHP Ryan Thompson from the 15-day injured list to the 60-day injured list. Right triceps inflammation. |
| 09/16/22 | Tampa Bay Rays activated LHP Brooks Raley from the restricted list. |
| 09/16/22 | Tampa Bay Rays optioned RHP Kevin Herget to Durham Bulls. |
| 09/16/22 | Tampa Bay Rays optioned OF Bligh Madris to Durham Bulls. |
| 09/16/22 | Tampa Bay Rays claimed OF Bligh Madris off waivers from Pittsburgh Pirates. |
| 09/15/22 | Tampa Bay Rays activated LHP Shane McClanahan from the 15-day injured list. |
| 09/15/22 | Tampa Bay Rays optioned LHP Josh Fleming to Durham Bulls. |
| 09/14/22 | Tampa Bay Rays optioned RHP Yonny Chirinos to Durham Bulls. |
| 09/13/22 | Tampa Bay Rays placed 2B Brandon Lowe on the 10-day injured list retroactive to September 12, 2022. Low back discomfort. |
| 09/13/22 | Tampa Bay Rays recalled LHP Josh Fleming from Durham Bulls. |
| 09/13/22 | RHP Cooper Criswell returned to Durham Bulls from Tampa Bay Rays. |
| 09/13/22 | Tampa Bay Rays recalled C Rene Pinto, and from Durham Bulls. |
| 09/13/22 | Tampa Bay Rays recalled RHP Yonny Chirinos from Durham Bulls. |
| 09/12/22 | RHP Cooper Criswell assigned to Tampa Bay Rays. |
| 09/12/22 | Tampa Bay Rays placed LHP Brooks Raley on the restricted list. |
| 09/12/22 | Tampa Bay Rays transferred LHP Brendan McKay from the 15-day injured list to the 60-day injured list. |
| 09/12/22 | Tampa Bay Rays signed free agent LHP Roberto Medina to a minor league contract. |
| 09/12/22 | Boston Red Sox claimed SS Yu Chang off waivers from Tampa Bay Rays. |
| 09/12/22 | Tampa Bay Rays optioned RHP Calvin Faucher to Durham Bulls. |
| 09/12/22 | Tampa Bay Rays selected the contract of RHP Javy Guerra from Durham Bulls. |
| 09/12/22 | Tampa Bay Rays selected the contract of RHP Cooper Criswell from Durham Bulls. |
| 09/12/22 | Tampa Bay Rays selected the contract of RHP Kevin Herget from Durham Bulls. |
| 09/12/22 | Tampa Bay Rays optioned RHP Luis Patino to Durham Bulls. |
| 09/09/22 | Tampa Bay Rays activated RHP Drew Rasmussen from the paternity list. |
| 09/09/22 | Tampa Bay Rays placed LHP Brendan McKay on the 15-day injured list. Tommy John surgery. |
| 09/09/22 | Tampa Bay Rays designated SS Yu Chang for assignment. |
| 09/09/22 | Tampa Bay Rays activated SS Wander Franco from the 10-day injured list. |
| 09/09/22 | Tampa Bay Rays recalled LHP Brendan McKay from Durham Bulls. |
| 09/09/22 | Tampa Bay Rays optioned RHP Yonny Chirinos to Durham Bulls. |
| 09/07/22 | Tampa Bay Rays sent RHP Tyler Glasnow on a rehab assignment to Durham Bulls. |
| 09/07/22 | Tampa Bay Rays activated 2B Brandon Lowe from the 10-day injured list. |
| 09/07/22 | Tampa Bay Rays released RHP Matt Wisler. |
| 09/07/22 | Tampa Bay Rays optioned 2B Vidal Brujan to Durham Bulls. |
| 09/06/22 | Tampa Bay Rays placed RHP Drew Rasmussen on the paternity list. |
| 09/06/22 | Tampa Bay Rays activated RHP Yonny Chirinos from the 60-day injured list. |
| 09/05/22 | Tampa Bay Rays designated RHP Matt Wisler for assignment. |
| 09/05/22 | Tampa Bay Rays recalled RHP Luis Patino from Durham Bulls. |
| 09/04/22 | Tampa Bay Rays sent SS Wander Franco on a rehab assignment to Durham Bulls. |
| 09/01/22 | Tampa Bay Rays recalled 2B Jonathan Aranda from Durham Bulls. |