Mariners Roster & Staff
Transactions
| Date | Transaction |
| 04/30/22 | Seattle Mariners signed free agent RHP Konner Wade to a minor league contract. |
| 04/30/22 | Seattle Mariners placed RF Mitch Haniger on the 10-day injured list. Right high ankle sprain. |
| 04/30/22 | Seattle Mariners recalled OF Stuart Fairchild from Tacoma Rainiers. |
| 04/29/22 | Seattle Mariners activated RF Mitch Haniger from the 10-day injured list. |
| 04/29/22 | Seattle Mariners designated RHP Matt Koch for assignment. |
| 04/28/22 | Seattle Mariners activated RHP Penn Murfee. |
| 04/28/22 | Seattle Mariners activated RHP Penn Murfee. |
| 04/28/22 | Seattle Mariners transferred 1B Evan White from the 10-day injured list to the 60-day injured list. Sports hernia. |
| 04/28/22 | Seattle Mariners recalled RHP Wyatt Mills from Tacoma Rainiers. |
| 04/28/22 | Seattle Mariners selected the contract of RHP Penn Murfee from Tacoma Rainiers. |
| 04/28/22 | Seattle Mariners optioned RHP Yohan Ramirez to Tacoma Rainiers. |
| 04/28/22 | Seattle Mariners optioned C Cal Raleigh to Tacoma Rainiers. |
| 04/27/22 | Seattle Mariners activated RHP Paul Sewald from the 10-day injured list. |
| 04/27/22 | RHP Penn Murfee returned to Tacoma Rainiers from Seattle Mariners. |
| 04/26/22 | Seattle Mariners traded 3B Kevin Padlo to San Francisco Giants for cash. |
| 04/25/22 | Seattle Mariners designated 1B Mike Ford for assignment. |
| 04/25/22 | Seattle Mariners placed C Luis Torrens on the 10-day injured list. Left shoulder inflammation. |
| 04/25/22 | Seattle Mariners activated C Luis Torrens from the 10-day injured list. |
| 04/25/22 | Seattle Mariners optioned 1B Mike Ford to Tacoma Rainiers. |
| 04/23/22 | Seattle Mariners designated 3B Kevin Padlo for assignment. |
| 04/23/22 | Arizona Diamondbacks traded OF Stuart Fairchild to Seattle Mariners for cash. |
| 04/22/22 | Seattle Mariners signed free agent RHP Jackson Sigman to a minor league contract. |
| 04/20/22 | Seattle Mariners placed RHP Paul Sewald on the 10-day injured list. |
| 04/20/22 | Seattle Mariners selected the contract of RHP Penn Murfee from Tacoma Rainiers. |
| 04/19/22 | Seattle Mariners placed C Luis Torrens on the 10-day injured list. |
| 04/19/22 | Seattle Mariners selected the contract of 1B Mike Ford from Tacoma Rainiers. |
| 04/17/22 | Seattle Mariners optioned RHP Riley O'Brien to Tacoma Rainiers. |
| 04/16/22 | Seattle Mariners placed RF Mitch Haniger on the 10-day injured list. |
| 04/16/22 | Seattle Mariners recalled 2B Donovan Walton from Tacoma Rainiers. |
| 04/13/22 | Seattle Mariners placed RHP Sergio Romo on the 10-day injured list retroactive to April 12, 2022. Right shoulder inflammation. |
| 04/13/22 | Seattle Mariners transferred RHP Casey Sadler from the 10-day injured list to the 60-day injured list. |
| 04/13/22 | Seattle Mariners selected the contract of RHP Matt Koch, and from Tacoma Rainiers. |
| 04/09/22 | RHP Daniel Ponce de Leon assigned to Seattle Mariners. |
| 04/09/22 | Seattle Mariners signed free agent LHP Nick Ramirez to a minor league contract. |
| 04/07/22 | Seattle Mariners placed 1B Evan White on the 10-day injured list. Sports hernia. |
| 04/07/22 | Seattle Mariners placed CF Kyle Lewis on the 10-day injured list. right meniscus tear. |
| 04/07/22 | Seattle Mariners placed RHP Casey Sadler on the 10-day injured list. Right shoulder labrum. |
| 04/07/22 | Seattle Mariners signed free agent C Adrian Garcia to a minor league contract. |
| 04/07/22 | Seattle Mariners placed RHP Ken Giles on the 10-day injured list. Right middle finger sprain. |
| 04/07/22 | Seattle Mariners selected the contract of RHP Matthew Festa, and from Tacoma Rainiers. |
| 04/07/22 | Baltimore Orioles traded SS Mason McCoy to Seattle Mariners. |
| 04/06/22 | Seattle Mariners signed free agent LHP Rob Kaminsky. |
| 04/06/22 | Seattle Mariners signed free agent 3B Taylor Featherston to a minor league contract. |
| 04/05/22 | RHP Abdiel Medina and assigned to Seattle Mariners. |
| 04/05/22 | Seattle Mariners optioned RHP Wyatt Mills to Tacoma Rainiers. |
| 04/04/22 | Seattle Mariners signed free agent LHP Austin Warner to a minor league contract. |
| 04/04/22 | LHP Jose Aquino and assigned to Seattle Mariners. |
| 04/04/22 | Seattle Mariners optioned 2B Donovan Walton to Tacoma Rainiers. |
| 04/03/22 | SS Edryn Rodriguez and assigned to Seattle Mariners. |
| 04/03/22 | RHP David Morillo and assigned to Seattle Mariners. |
| 04/03/22 | RHP Dutch Landis and assigned to Seattle Mariners. |
| 04/03/22 | LHP Blake Townsend and assigned to Seattle Mariners. |
| 04/03/22 | SS Carlos Fernandez and assigned to Seattle Mariners. |
| 04/03/22 | CF Arturo Guerrero assigned to Seattle Mariners. |
| 04/03/22 | RHP Chris Jefferson and assigned to Seattle Mariners. |
| 04/03/22 | C Ty Duvall and assigned to Seattle Mariners. |
| 04/03/22 | CF Arturo Guerrero roster status changed by Seattle Mariners. |
| 04/03/22 | LHP Danny Chang and assigned to Seattle Mariners. |
| 04/03/22 | SS Juan Querecuto and assigned to Seattle Mariners. |
| 04/03/22 | C Junior Gonzalez and assigned to Seattle Mariners. |
| 04/03/22 | Seattle Mariners optioned LHP Nick Margevicius to Tacoma Rainiers. |
| 04/02/22 | RHP Tyler Driver and assigned to Seattle Mariners. |
| 04/02/22 | Seattle Mariners signed free agent RHP Connor Jones to a minor league contract. |
| 04/02/22 | RHP Luis Curvelo and assigned to Seattle Mariners. |
| 04/02/22 | Seattle Mariners released C Chance Sisco. |
| 04/01/22 | SS Miguel Perez assigned to Seattle Mariners. |
| 04/01/22 | RHP Kyle Hill and assigned to Seattle Mariners. |
| 04/01/22 | LHP Tommy Milone elected free agency. |
| 04/01/22 | LHP Tommy Milone roster status changed by Seattle Mariners. |
| 04/01/22 | SS Miguel Perez roster status changed by Seattle Mariners. |
| 04/01/22 | Seattle Mariners signed free agent RHP Mike Mokma to a minor league contract. |