Brewers Roster & Staff
Transactions
| Date | Transaction |
| 05/31/22 | Milwaukee Brewers optioned LHP Ethan Small to Nashville Sounds. |
| 05/31/22 | Milwaukee Brewers optioned 2B Mark Mathias to Nashville Sounds. |
| 05/30/22 | Milwaukee Brewers transferred RHP Justin Topa from the 10-day injured list to the 60-day injured list. |
| 05/30/22 | Milwaukee Brewers sent SS Willy Adames on a rehab assignment to Nashville Sounds. |
| 05/30/22 | Milwaukee Brewers placed RHP Brandon Woodruff on the 15-day injured list retroactive to May 28, 2022. Right ankle sprain. |
| 05/30/22 | Milwaukee Brewers selected the contract of RHP Luke Barker from Nashville Sounds. |
| 05/30/22 | Texas Rangers traded 2B Jose Acosta to Milwaukee Brewers. |
| 05/30/22 | Milwaukee Brewers selected the contract of LHP Ethan Small from Nashville Sounds. |
| 05/30/22 | Milwaukee Brewers selected the contract of RHP Peter Strzelecki from Nashville Sounds. |
| 05/29/22 | Milwaukee Brewers sent SS Willy Adames on a rehab assignment to Carolina Mudcats. |
| 05/28/22 | Milwaukee Brewers placed RHP Luis Perdomo on the 15-day injured list. Right elbow effusion. |
| 05/28/22 | Milwaukee Brewers recalled RHP Miguel Sanchez from Nashville Sounds. |
| 05/26/22 | Milwaukee Brewers activated LHP Josh Hader. |
| 05/26/22 | Milwaukee Brewers optioned RHP Miguel Sanchez to Nashville Sounds. |
| 05/25/22 | Milwaukee Brewers signed free agent RHP Roman Perez to a minor league contract. |
| 05/24/22 | Milwaukee Brewers placed RF Hunter Renfroe on the 10-day injured list. Right hamstring strain. |
| 05/24/22 | Milwaukee Brewers selected the contract of 2B Mark Mathias from Nashville Sounds. |
| 05/23/22 | Milwaukee Brewers placed RHP Freddy Peralta on the 15-day injured list. Strained right lat. |
| 05/23/22 | LHP Josh Hader roster status changed by Milwaukee Brewers. |
| 05/23/22 | Milwaukee Brewers recalled RHP Trevor Kelley from Nashville Sounds. |
| 05/23/22 | Milwaukee Brewers recalled RHP Miguel Sanchez from Nashville Sounds. |
| 05/23/22 | Milwaukee Brewers sent RHP Dylan File outright to Nashville Sounds. |
| 05/20/22 | Milwaukee Brewers activated CF Andrew McCutchen from the 10-day injured list. |
| 05/20/22 | Milwaukee Brewers optioned RHP Trevor Kelley to Nashville Sounds. |
| 05/19/22 | Milwaukee Brewers sent RHP Alec Bettinger outright to Nashville Sounds. |
| 05/18/22 | Milwaukee Brewers placed SS Willy Adames on the 10-day injured list retroactive to May 16, 2022. High left ankle sprain. |
| 05/18/22 | Milwaukee Brewers recalled 2B Keston Hiura from Nashville Sounds. |
| 05/17/22 | Milwaukee Brewers placed RHP J.C. Mejia on the restricted list. |
| 05/17/22 | Milwaukee Brewers signed free agent RHP Cristofher Carrasco to a minor league contract. |
| 05/17/22 | Milwaukee Brewers selected the contract of RHP Trevor Kelley from Nashville Sounds. |
| 05/16/22 | Milwaukee Brewers activated LHP Brent Suter from the paternity list. |
| 05/16/22 | Milwaukee Brewers placed RHP Jandel Gustave on the 15-day injured list retroactive to May 15, 2022. Right hamstring strain. |
| 05/13/22 | Milwaukee Brewers placed LHP Brent Suter on the paternity list. |
| 05/13/22 | Milwaukee Brewers recalled RHP Jandel Gustave from Nashville Sounds. |
| 05/10/22 | Milwaukee Brewers optioned RHP Jandel Gustave to Nashville Sounds. |
| 05/10/22 | Milwaukee Brewers recalled RHP J.C. Mejia from Nashville Sounds. |
| 05/09/22 | Milwaukee Brewers activated RHP Alec Bettinger. |
| 05/09/22 | Milwaukee Brewers sent RHP Jose Urena outright to Nashville Sounds. |
| 05/07/22 | Milwaukee Brewers placed CF Andrew McCutchen on the 10-day injured list. |
| 05/07/22 | Milwaukee Brewers recalled 3B Mike Brosseau from Nashville Sounds. |
| 05/06/22 | Milwaukee Brewers selected the contract of RHP Luis Perdomo from Nashville Sounds. |
| 05/06/22 | Milwaukee Brewers optioned 2B Keston Hiura to Nashville Sounds. |
| 05/02/22 | Milwaukee Brewers designated RHP Jose Urena for assignment. |
| 05/02/22 | Milwaukee Brewers activated 3B Luis Urías from the 10-day injured list. |
| 05/02/22 | Milwaukee Brewers optioned C Alex Jackson to Nashville Sounds. |
| 05/02/22 | Milwaukee Brewers optioned 3B Mike Brosseau to Nashville Sounds. |
| 05/01/22 | Milwaukee Brewers placed RHP Jake Cousins on the 10-day injured list. Right elbow effusion. |
| 05/01/22 | Milwaukee Brewers activated C Victor Caratini from the 10-day injured list. |