Red Sox Roster & Staff
Transactions
| Date | Transaction |
| 05/30/22 | Boston Red Sox placed LHP Matt Strahm on the 10-day injured list. |
| 05/30/22 | Boston Red Sox recalled RHP Hirokazu Sawamura from Worcester Red Sox. |
| 05/29/22 | RHP Josh Winckowski returned to Worcester Red Sox from Boston Red Sox. |
| 05/28/22 | Boston Red Sox placed RHP Hansel Robles on the 15-day injured list retroactive to May 25, 2022. Back spasms. |
| 05/28/22 | Boston Red Sox optioned RHP Hirokazu Sawamura to Worcester Red Sox. |
| 05/28/22 | Boston Red Sox recalled RHP Ryan Brasier, and from Worcester Red Sox. |
| 05/28/22 | Boston Red Sox recalled RHP Phillips Valdez from Worcester Red Sox. |
| 05/28/22 | Boston Red Sox recalled RHP Josh Winckowski from Worcester Red Sox. |
| 05/25/22 | Boston Red Sox signed free agent C Anger Romero to a minor league contract. |
| 05/25/22 | Boston Red Sox signed free agent RHP Brett Kennedy to a minor league contract. |
| 05/24/22 | Boston Red Sox placed RHP Hansel Robles on the 15-day injured list. |
| 05/24/22 | Boston Red Sox purchased RHP Brett Kennedy from Long Island Ducks. |
| 05/20/22 | Boston Red Sox activated RHP Michael Wacha from the 15-day injured list. |
| 05/20/22 | Boston Red Sox optioned RHP Ryan Brasier to Worcester Red Sox. |
| 05/19/22 | Boston Red Sox signed free agent SS Marvin Alcantara to a minor league contract. |
| 05/18/22 | Boston Red Sox sent RF Jaylin Davis outright to Worcester Red Sox. |
| 05/14/22 | Boston Red Sox designated RF Jaylin Davis for assignment. |
| 05/14/22 | Boston Red Sox activated LHP Rich Hill from the 10-day injured list. |
| 05/14/22 | Boston Red Sox optioned RHP Kutter Crawford to Worcester Red Sox. |
| 05/12/22 | Boston Red Sox placed LHP Josh Taylor on the 60-day injured list. Low back strain,. |
| 05/12/22 | Boston Red Sox optioned SS Jonathan Arauz to Worcester Red Sox. |
| 05/09/22 | Boston Red Sox signed free agent RHP Carlos Mendoza to a minor league contract. |
| 05/08/22 | Boston Red Sox placed RHP Michael Wacha on the 15-day injured list retroactive to May 5, 2022. Left intercostal irritation. |
| 05/08/22 | Boston Red Sox recalled RHP Tyler Danish from Worcester Red Sox. |
| 05/07/22 | Boston Red Sox signed free agent RHP Carlos Martinez to a minor league contract. |
| 05/07/22 | Boston Red Sox activated CF Enrique Hernandez from the 10-day injured list. |
| 05/07/22 | Boston Red Sox optioned 2B Jarren Duran to Worcester Red Sox. |
| 05/06/22 | Boston Red Sox placed CF Enrique Hernandez on the 10-day injured list. |
| 05/06/22 | Boston Red Sox placed LHP Rich Hill on the 10-day injured list. |
| 05/06/22 | Boston Red Sox selected the contract of RHP John Schreiber, and from Worcester Red Sox. |
| 05/06/22 | Boston Red Sox recalled 2B Jarren Duran from Worcester Red Sox. |
| 05/02/22 | Boston Red Sox optioned RHP Phillips Valdez to Worcester Red Sox. |
| 05/02/22 | Boston Red Sox optioned RF Jaylin Davis to Worcester Red Sox. |
| 05/01/22 | Boston Red Sox sent SS Jonathan Arauz on a rehab assignment to Worcester Red Sox. |
| 05/01/22 | Boston Red Sox sent 3B Travis Shaw outright to Worcester Red Sox. |