Pirates Roster & Staff
Transactions
| Date | Transaction |
| 06/30/22 | Pittsburgh Pirates activated SS Tucupita Marcano. |
| 06/30/22 | Pittsburgh Pirates designated SS Yu Chang for assignment. |
| 06/28/22 | Pittsburgh Pirates sent LHP Dillon Peters on a rehab assignment to Altoona Curve. |
| 06/28/22 | Pittsburgh Pirates sent LHP Dillon Peters on a rehab assignment to Altoona Curve. |
| 06/28/22 | Pittsburgh Pirates sent SS Tucupita Marcano on a rehab assignment to Altoona Curve. |
| 06/28/22 | Pittsburgh Pirates sent RHP Nick Mears on a rehab assignment to Indianapolis Indians. |
| 06/28/22 | Pittsburgh Pirates sent CF Jake Marisnick on a rehab assignment to Indianapolis Indians. |
| 06/28/22 | Pittsburgh Pirates sent RHP Nick Mears on a rehab assignment to Bradenton Marauders. |
| 06/28/22 | Pittsburgh Pirates sent LHP Dillon Peters on a rehab assignment to Altoona Curve. |
| 06/28/22 | Pittsburgh Pirates sent CF Jake Marisnick on a rehab assignment to Indianapolis Indians. |
| 06/28/22 | Pittsburgh Pirates sent RHP Duane Underwood Jr. on a rehab assignment to Altoona Curve. |
| 06/28/22 | Pittsburgh Pirates optioned RHP Miguel Yajure to Indianapolis Indians. |
| 06/28/22 | Pittsburgh Pirates recalled LHP Aaron Fletcher from Indianapolis Indians. |
| 06/27/22 | Pittsburgh Pirates designated LHP Anthony Banda for assignment. |
| 06/27/22 | Pittsburgh Pirates activated 2B Josh VanMeter. |
| 06/27/22 | Pittsburgh Pirates optioned OF Cal Mitchell to Indianapolis Indians. |
| 06/27/22 | Pittsburgh Pirates recalled RHP Miguel Yajure from Indianapolis Indians. |
| 06/26/22 | Pittsburgh Pirates sent SS Tucupita Marcano on a rehab assignment to Bradenton Marauders. |
| 06/26/22 | Pittsburgh Pirates released RHP Heath Hembree. |
| 06/26/22 | Pittsburgh Pirates sent RHP Jerad Eickhoff outright to Indianapolis Indians. |
| 06/25/22 | Pittsburgh Pirates transferred RHP Max Kranick from the 7-day injured list to the 60-day injured list. |
| 06/25/22 | Pittsburgh Pirates recalled RHP Max Kranick from Indianapolis Indians. |
| 06/24/22 | Pittsburgh Pirates designated RHP Jerad Eickhoff for assignment. |
| 06/24/22 | Pittsburgh Pirates activated RHP Austin Brice. |
| 06/24/22 | Pittsburgh Pirates selected the contract of RHP Austin Brice from Indianapolis Indians. |
| 06/23/22 | Pittsburgh Pirates sent RF Ben Gamel on a rehab assignment to Indianapolis Indians. |
| 06/22/22 | Pittsburgh Pirates designated RHP Heath Hembree for assignment. |
| 06/22/22 | Pittsburgh Pirates transferred CF Jake Marisnick from the 10-day injured list to the 60-day injured list. |
| 06/22/22 | Pittsburgh Pirates selected the contract of RHP Jerad Eickhoff from Indianapolis Indians. |
| 06/21/22 | Pittsburgh Pirates sent LF Yoshi Tsutsugo on a rehab assignment to Indianapolis Indians. |
| 06/21/22 | Pittsburgh Pirates sent SS Kevin Newman on a rehab assignment to Indianapolis Indians. |
| 06/21/22 | Pittsburgh Pirates sent 2B Josh VanMeter on a rehab assignment to Indianapolis Indians. |
| 06/21/22 | Pittsburgh Pirates optioned LHP Eric Stout to Indianapolis Indians. |
| 06/21/22 | Chicago Cubs traded LHP Eric Stout to Pittsburgh Pirates for cash. |
| 06/20/22 | Pittsburgh Pirates activated OF Bligh Madris. |
| 06/20/22 | Pittsburgh Pirates placed RHP Zach Thompson on the 15-day injured list retroactive to June 18, 2022. Right forearm never inflammation. |
| 06/20/22 | Pittsburgh Pirates optioned SS Liover Peguero to Altoona Curve. |
| 06/20/22 | Pittsburgh Pirates selected the contract of OF Bligh Madris from Indianapolis Indians. |
| 06/20/22 | Pittsburgh Pirates recalled 3B Oneil Cruz, and from Indianapolis Indians. |
| 06/17/22 | Pittsburgh Pirates placed SS Tucupita Marcano on the 10-day injured list. |
| 06/17/22 | Pittsburgh Pirates placed CF Canaan Smith-Njigba on the 60-day injured list retroactive to June 15, 2022. Right wrist fracture. |
| 06/17/22 | Pittsburgh Pirates selected the contract of LHP Cam Vieaux from Indianapolis Indians. |
| 06/17/22 | Pittsburgh Pirates recalled SS Liover Peguero from Altoona Curve. |
| 06/15/22 | Pittsburgh Pirates optioned RHP Bryse Wilson to Indianapolis Indians. |
| 06/14/22 | Pittsburgh Pirates activated RHP Heath Hembree. |
| 06/14/22 | Pittsburgh Pirates recalled RHP Bryse Wilson from Indianapolis Indians. |
| 06/14/22 | Pittsburgh Pirates optioned C Jason Delay to Indianapolis Indians. |
| 06/13/22 | Pittsburgh Pirates placed RHP Duane Underwood Jr. on the 10-day injured list. |
| 06/13/22 | Pittsburgh Pirates recalled SS Hoy Park from Indianapolis Indians. |
| 06/13/22 | Pittsburgh Pirates optioned LHP Aaron Fletcher to Indianapolis Indians. |
| 06/13/22 | Pittsburgh Pirates selected the contract of C Jason Delay from Indianapolis Indians. |
| 06/13/22 | Pittsburgh Pirates recalled CF Canaan Smith-Njigba from Indianapolis Indians. |
| 06/13/22 | Pittsburgh Pirates recalled OF Travis Swaggerty and from Indianapolis Indians. |
| 06/13/22 | Pittsburgh Pirates optioned OF Travis Swaggerty to Indianapolis Indians. |
| 06/08/22 | Pittsburgh Pirates sent RHP Heath Hembree on a rehab assignment to Indianapolis Indians. |
| 06/07/22 | Pittsburgh Pirates sent RHP Nick Mears on a rehab assignment to Indianapolis Indians. |
| 06/07/22 | Pittsburgh Pirates sent RHP Nick Mears on a rehab assignment to Indianapolis Indians. |
| 06/07/22 | Pittsburgh Pirates recalled LHP Aaron Fletcher from Indianapolis Indians. |
| 06/06/22 | Pittsburgh Pirates placed LHP Dillon Peters on the 15-day injured list retroactive to June 3, 2022. |
| 06/05/22 | Pittsburgh Pirates recalled SS Rodolfo Castro and from Indianapolis Indians. |
| 06/05/22 | Arizona Diamondbacks claimed SS Cole Tucker and off waivers from Pittsburgh Pirates. |
| 06/05/22 | Pittsburgh Pirates optioned SS Rodolfo Castro to Indianapolis Indians. |
| 06/03/22 | Pittsburgh Pirates activated 1B Daniel Vogelbach from the 10-day injured list. |
| 06/03/22 | Pittsburgh Pirates placed 2B Josh VanMeter on the 10-day injured list retroactive to June 2, 2022. Left ring finger fracture. |