BOSTON -- The Yankees’ double-digit cushion in the American League East did little to mask their disappointment on Saturday evening, particularly in Wandy Peralta’s corner of the visiting clubhouse at Fenway Park, where the reliever was still smoldering after surrendering a walk-off hit.

When Anthony Rizzo looked around and remarked, “These are the types of games we lose,” it was intended as a compliment. These Yankees are confident that they will prevail in any tight game -- even though they did not in this one, with Alex Verdugo’s 10th-inning hit sending the Bombers to a 6-5 loss.

“Credit to the Boston hitters; they had really good at-bats and didn’t try to do too much,” Rizzo said. “They got hits when they needed to. We believe in our bullpen. Our team is built on pitching and defense. We’ve just got to bounce back tomorrow.”

Usually, it’s the Yankees who are kings of the comeback, but they were walked off for the fourth time this year -- falling to 5-2 in extra-inning games. Their lockdown relief corps had produced a stellar 48-0 record when leading after seven innings, but Clay Holmes suffered his second blown save and Peralta stumbled in the 10th.

“It feels terrible,” Peralta said through an interpreter. “For us, when we go in the game, we want to do the best we can out there. We want to battle and do our job. Today, that wasn’t the case.”

Aaron Hicks hit his third homer in four games before Rizzo and Josh Donaldson stroked run-scoring hits, building a two-run advantage that was down to a one-run lead in the eighth. Holmes entered for a four-out save chance with a runner on second after Michael King worked two innings in relief of starter Jordan Montgomery.

Holmes -- a likely American League All-Star -- walked Xander Bogaerts before getting ahead of Verdugo with an 0-2 count. The sinkerballer induced the brand of contact he’d hoped for, a routine grounder to the shortstop position, but Verdugo’s knock skipped through the shifted infield as Boston tied the game.

“They’re so good. No one is perfect,” Montgomery said. “Clay gave up an infield hit. If we don’t shift, that’s a routine play. Verdugo just hit it where we weren’t. He might have been trying to do that. It’s a good piece of hitting if he was.”

New York punched back in the top of the 10th, with Aaron Judge and Rizzo belting RBI doubles off Jake Diekman, but Rizzo was caught stealing third before Giancarlo Stanton struck out for the fourth time in the game.

Yankees manager Aaron Boone said that he was fine with Rizzo’s aggressive baserunning, and Rizzo said that he would take the same chance again in a similar opportunity.

“I thought I had a good jump,” Rizzo said.

Peralta had not allowed a run over his previous seven outings (since June 20), retiring 20 of 27 batters faced, but Boston squared him up. Rob Refsnyder opened the 10th with a single and rookie Jeter Downs -- yes, named for that Jeter -- collected his first Major League hit and RBI with a knock to right field.

Xander Bogaerts followed with a chopper that third baseman Josh Donaldson couldn’t handle cleanly, a probable double-play ball that forced the Yanks to settle for one out. Donaldson had made stellar defensive plays in the second and ninth innings, but the bobble gave Verdugo a chance to bat.

“We’re thinking double play there,” Boone said. “I thought it was a great recovery just to get the out at first, but I think in the transfer, he lost it. He’s been so special over there. Between him and DJ [LeMahieu], there hasn’t been a better third-base combo out there.”

Peralta whipped his head toward right field to watch after Verdugo barreled a sinker, two runs racing home. As Rizzo said, these seem to be the kind of games that the Yankees lose. Fortunately for them, it doesn’t happen very often.

“He was able to beat us tonight,” Peralta said of Verdugo. “I’m sure we will have another go at it at some point during the season.”