CHICAGO -- The White Sox did not win Saturday at Guaranteed Rate Field, falling by an 8-4 final to the Yankees.

They did not surpass the .500 mark for the season after arriving there with two wins to start this four-game series. They also didn’t go quietly.

Trailing by a 7-0 margin entering the eighth, they scored four runs off of Nestor Cortes Jr. and Jonathan Holder to force closer Aroldis Chapman into action in the ninth. James McCann knocked out his fifth home run, coming against Holder, a three-run shot to right-center following three strikeouts in his first three at-bats.

• Box score

Even in a non-save situation, the White Sox had two connections off of the hard-throwing Chapman with a 99.5 mph exit velocity or greater. But they still couldn’t avoid just their third loss in the last 12 home games.

“That shows the fight in this clubhouse. Down 7-0, guys weren't rolling over,” McCann said. “We punched out however many times, had a lot of good at-bats, so guys coming through with their third, fourth at-bats, making them count.”

“They continued to play obviously,” White Sox manager Rick Renteria said. “Mac’s homer, the guys getting on base. They didn’t give up. They continued to try to do what they can.”

Saturday night actually was set up perfectly for the White Sox.

A raucous sellout crowd of 36,074 was in attendance, marking the team’s second sellout of the season and first since May 5 against Boston, and the dire weather forecast for the evening was reduced to a 32-minute rain delay at the start. But the setback prevented the White Sox from going above .500 for the first time since April 4, 2018 -- when they were 3-2 -- dropping them to 34-35 overall.

Reynaldo López held the Yankees scoreless for the first three innings before allowing four runs in the fourth. Gary Sanchez doubled home two runs and Gleyber Torres launched a two-run home run, giving him 15 for the season. The Yankees added one in the sixth, two in the seventh and one in the ninth to break the White Sox three-game winning streak.

Lopez finished with five runs allowed on six hits over six innings, with four strikeouts and two walks. Lopez allowed at least five earned runs for the seventh time in 15 starts, struggling with a curveball used as a solid weapon in his win last Sunday at Kansas City but only thrown eight times among his 97 pitches Saturday.

Postgame reviews of Lopez’s work were positive, despite the loss and his 6.31 ERA overall.

“Again the numbers didn’t look good,” Renteria said. “Yeah, we lost the ballgame, but there’s hope for this young man. He’s going to be pretty good. Our patience and his patience to get over the hump are going to be very, very important. I’m not giving up on him.”

“I can’t say that, because I had just one bad inning, the outing was bad,” said Lopez through interpreter Billy Russo. “No. It was just one bad inning and I felt good, honestly.”

White Sox catcher Welington Castillo and Renteria were ejected by home-plate umpire Phil Cuzzi for arguing balls and strikes in the eighth. McCann started the game at designated hitter, meaning the White Sox lost the DH with the ejection and McCann taking over behind the plate.

Renteria was ejected for the fourth time in 2019 and 23rd for his career, and it was the second for Castillo. The White Sox offense struck out 16 times against four New York relievers, with Chad Green getting the spot start and fanning six in the first two innings, and Chapman striking out Ryan Cordell to end the night and the bid to push above break-even.

“It's how you bounce back. And it doesn't mean you're going to win tomorrow, either,” McCann said. “It's just, how do you handle a defeat? How do you handle a bad at-bat? How do you handle a bad outing? Whatever it may be.

“But it doesn't mean that we step back and say, 'Oh, we're back under .500, we're supposed to lose.' We expect to win when we show up to the ballpark. You can take learning experiences whether you win or lose.”