MIAMI -- With his team trailing by four runs in the sixth inning, Marlins manager Don Mattingly’s frustration level rose on a low fastball that was called a strike with Jorge Alfaro at the plate.

Unhappy with the call, Mattingly let off some steam on home-plate umpire Jeff Nelson, and drew an ejection, part of a frustrating overall night in which the Marlins lost, 7-2, to the Braves on Friday at Marlins Park.

Mattingly took issue on Braves’ right-hander Touki Toussaint’s 93.1 mph fastball that, according to MLB’s Gameday tracking, was low and should have been ball four.

“I was just frustrated by that whole sequence of events, because it happened the inning before,” said Mattingly, ejected for the 30th time in his career. “Then that happens.”

Mattingly’s reference was to the top of the sixth, when Brian McCann’s two-run home run broke open a 5-1 Atlanta lead. Before the blast, Jose Urena’s 1-2 borderline inside fastball was called ball two. Alfaro motioned to the Miami dugout that he felt the pitch should have been strike three, although it was certainly close.

“I was just frustrated more by the McCann miss,” Mattingly said. “Alfaro gives me the sign that McCann's out basically on the two-strike fastball in. Then he hits a two-run homer. We're in the game, and Jose is keeping us in there at 3-1. Then it goes to 5-1. You feel it cost you two runs there, and then you feel like you get a ball four. You feel like it's really down.”

The game had already included a couple of ejections on the Braves’ side when Mattingly was tossed for the first time this season.

In the second inning, Atlanta right-hander Kevin Gausman threw a fastball that sailed behind Urena with runners on second and third. Nelson ejected Gausman, and Braves manager Brian Snitker also was tossed because Nelson felt there was intent.

There was some history between the clubs dating back to Aug. 15, 2018, at SunTrust Park, where Urena struck Ronald Acuna Jr. with his first pitch of the game.

Urena was ejected on that day, and MLB slapped the Miami right-hander with a six-game suspension.

Friday was the first time Urena faced the Braves since the incident.

After Mattingly was tossed in the sixth inning, Alfaro ended up getting a single, and the Marlins pushed across a run when pinch-hitter Neil Walker drew a bases-loaded walk.

“It's not easy back there,” Mattingly said. “I'm sure he's trying to get 'em right. They are missing them both ways every day. It's not just us.”