The Angels have endured more than a few heartbreaking losses this season, but Friday's 8-4 walk-off defeat to the Rockies at Coors Field might've topped them all.

After Jared Walsh hit a solo homer in the eighth to tie the game and Anthony Bemboom smacked a go-ahead solo shot in the ninth, reliever Ty Buttrey couldn't hold the lead, allowing a solo homer to Ryan McMahon before José Quijada served up a grand slam to Charlie Blackmon. It was yet another blow to the Angels’ slim postseason chances, as they fell to 4 1/2 games behind the Astros for second place in the American League West with 14 games remaining.

• Box score

"Boomer hits the home run and sometimes you think, 'All right, game's over,' and unfortunately it just kind of punches you in the face like that," Buttrey said. "That's just how baseball is. You think you got it and it's not over until the last out is made."

It was the fourth blown save by Buttrey and the Major League-leading 13th by the Angels. Buttrey gave up the game-tying homer to McMahon with one out and then a double to Josh Fuentes before issuing an intentional walk. Quijada struck out Raimel Tapia but walked Trevor Story with two outs and then gave up the game-winning blast on a 3-1 fastball to Blackmon.

“The pitch wasn't awful to McMahon, but then the double from Fuentes, and then we could just see it was not trending right,” Maddon said. “We got the punchout on Tapia. Story, we kind of pitched around right there. Getting behind Blackmon, that's what put him in position to hit that home run. It ended up being a grand slam, but again, this is the frustrating part of our season. We've been in this position often, and we've been unable to close games.”

Walsh has been one of the club's hottest hitters this month and kept it rolling with a solo blast on a 1-0 fastball from Mychal Givens to tie it in the eighth. It was Walsh's third straight game with a homer and he has four over his last six games.

But Bemboom was the hero briefly with one out in the ninth, crushing a go-ahead blast off reliever Daniel Bard, the brother of Angels reliever Luke Bard. It was Bemboom’s second homer of the season and the third of his career, and it came on a first-pitch fastball.

• Notes: David Fletcher near return; Brandon Marsh trying first base

It helped right-hander Griffin Canning avoid getting the loss on a night in which he pitched well but wasn’t helped by his defense. Canning allowed three runs on seven hits over 5 2/3 innings in a no-decision.

Canning ran into trouble in the third inning after the Angels spotted him an early lead with two runs in the first against Germán Márquez. Canning allowed a single to Fuentes and a walk to Tony Wolters to open the inning before getting Tapia to fly out to left.

Story then smacked a ball into the right-center-field gap, and center fielder Mike Trout and right fielder Taylor Ward appeared to have some miscommunication. Ward ran in front of Trout and the ball hit off Trout’s glove for what was ruled an RBI double. Blackmon followed with a sacrifice fly to tie the game.

"Taylor said he should've called it, but did not," Maddon said. "Mike called it at the very end and I think that's where the confusion was. Taylor should've called it sooner, he definitely had a bead on it and he would've been able to make that catch."

Canning was the victim of yet another two-out rally in the fifth, when he gave up a single to Tapia. Story followed with a deep drive to right field that Ward couldn’t handle for an RBI triple. Ward made a leaping attempt but came up short, as it looked like he lost track of where the fence began, not accounting for a ledge sticking out of the wall.

"This is a tough place to play the outfield,” Canning said. “The outfield is very big and there's a lot of ground to cover. And you factor in that right-field wall, and it's a tough place to play if you've never been here.”