Astros Roster & Staff
Transactions
| Date | Transaction |
| 06/29/12 | Bud Norris roster status changed by Houston Astros. |
| 06/29/12 | Houston Astros signed free agent OF Hector Roa to a minor league contract. |
| 06/29/12 | Houston Astros optioned Xavier Cedeno to Oklahoma City RedHawks. |
| 06/28/12 | Rio Ruiz assigned to GCL Astros from Houston Astros. |
| 06/28/12 | RHP Rauldison Rodriguez assigned to DSL Astros from Houston Astros. |
| 06/28/12 | Tyler Heineman assigned to Tri-City ValleyCats from Houston Astros. |
| 06/27/12 | Houston Astros sent LF Travis Buck outright to Oklahoma City RedHawks. |
| 06/26/12 | Houston Astros optioned Fernando Martinez to Oklahoma City RedHawks. |
| 06/26/12 | Houston Astros signed SS Nolan Fontana. |
| 06/26/12 | Houston Astros placed CF Justin Maxwell on the 15-day disabled list. Loose bodies in left ankle. |
| 06/26/12 | Houston Astros designated Travis Buck for assignment. |
| 06/26/12 | Houston Astros selected the contract of Scott Moore from Oklahoma City RedHawks. |
| 06/25/12 | Houston Astros signed 3B Rio Ruiz. |
| 06/23/12 | Houston Astros placed RF Fernando Martinez on the 15-day disabled list. |
| 06/22/12 | Houston Astros signed C Tyler Heineman. |
| 06/20/12 | RHP Hector Ambriz assigned to Oklahoma City RedHawks from Houston Astros. |
| 06/19/12 | Houston Astros signed free agent RHP Hector Ambriz to a minor league contract. |
| 06/18/12 | Houston Astros signed RHP Lance McCullers. |
| 06/17/12 | Carlos Lee roster status changed by Houston Astros. |
| 06/17/12 | Houston Astros selected the contract of Dallas Keuchel from Oklahoma City RedHawks. |
| 06/17/12 | Houston Astros optioned Brett Wallace to Oklahoma City RedHawks. |
| 06/17/12 | Houston Astros placed RHP Bud Norris on the 15-day disabled list retroactive to June 13, 2012. Left knee sprain |
| 06/17/12 | Sergio Escalona roster status changed by Houston Astros. |
| 06/17/12 | Houston Astros signed RHP Mike Hauschild. |
| 06/17/12 | Houston Astros signed 1B Michael Martinez. |
| 06/15/12 | Houston Astros placed RHP Wilton Lopez on the 15-day disabled list retroactive to June 11, 2012. Sprained right elbow. |
| 06/15/12 | Houston Astros signed free agent RHP Rauldison Rodriguez to a minor league contract. |
| 06/15/12 | Fernando Abad roster status changed by Houston Astros. |
| 06/13/12 | Houston Astros signed RHP Travis Ballew. |
| 06/13/12 | Houston Astros signed LHP Kenny Long. |
| 06/13/12 | Houston Astros signed LHP Joe Bircher. |
| 06/13/12 | Houston Astros signed OF Marc Wik. |
| 06/13/12 | Houston Astros signed free agent SS Brian Blasik to a minor league contract. |
| 06/13/12 | Houston Astros signed SS Ryan Dineen. |
| 06/13/12 | Houston Astros signed OF Brett Phillips. |
| 06/09/12 | Fernando Martinez roster status changed by Houston Astros. |
| 06/09/12 | Houston Astros signed RHP Christian Garcia. |
| 06/09/12 | Houston Astros signed 3B Angel Ibanez. |
| 06/09/12 | Houston Astros signed IF Austin Elkins. |
| 06/09/12 | Houston Astros signed RHP Aaron West. |
| 06/09/12 | Houston Astros signed OF Dan Gulbransen. |
| 06/09/12 | Houston Astros signed RHP Daniel Minor. |
| 06/09/12 | Houston Astros recalled Matt Downs from Oklahoma City RedHawks. |
| 06/09/12 | Houston Astros signed RHP Jordan Jankowski. |
| 06/09/12 | Houston Astros signed RHP Michael Dimock. |
| 06/08/12 | Houston Astros placed SS Marwin Gonzalez on the 15-day disabled list retroactive to June 7, 2012. Bruised right heel. |
| 06/08/12 | Houston Astros recalled Brian Bixler from Oklahoma City RedHawks. |
| 06/08/12 | Houston Astros signed RHP Erick Gonzalez. |
| 06/08/12 | Houston Astros signed C MP Cokinos. |
| 06/08/12 | Houston Astros signed RHP John Neely. |
| 06/08/12 | Houston Astros signed OF Andrew Aplin. |
| 06/08/12 | Houston Astros signed OF Terrell Joyce. |
| 06/08/12 | Houston Astros signed LHP Brian Holmes. |
| 06/08/12 | Houston Astros signed SS Joe Sclafani. |
| 06/08/12 | Houston Astros signed C Ricky Gingras. |
| 06/07/12 | Houston Astros signed SS Carlos Correa. |
| 06/06/12 | Houston Astros signed RHP Brady Rodgers. |
| 06/03/12 | Houston Astros recalled Brett Wallace from Oklahoma City RedHawks. |
| 06/03/12 | Houston Astros recalled Jordan Lyles from Oklahoma City RedHawks. |
| 06/03/12 | Houston Astros optioned Matt Downs to Oklahoma City RedHawks. |
| 06/03/12 | Houston Astros placed 1B Carlos Lee on the 15-day disabled list retroactive to June 2, 2012. Strained left hamstring. |
| 06/02/12 | Houston Astros recalled RF Fernando Martinez from Oklahoma City RedHawks. |
| 06/02/12 | Houston Astros placed LF Travis Buck on the 15-day disabled list retroactive to May 29, 2012. Right Achilles tendinitis. |